Ovine IL-17A ELISA Kit ELISA试剂盒,Ovine IL-17A ELISA Kit/绵羊IL-17A ELISA试剂盒-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Ovine IL-17A ELISA Kit ELISA试剂盒,Ovine IL-17A ELISA Kit/绵羊IL-17A ELISA试剂盒

2024-10-24

Ovine IL-17A ELISA Kit/绵羊IL-17A ELISA试剂盒

货号：ESH3RB,ESH3RBX5

规格：96 Tests,5X96 Tests

价格：6641,29884

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：山羊

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	0.45 pg/mL
检测范围	0.45-100 pg/mL
样本类型/体积	血清 50 μL 血浆 50 μL 上清液 50 μL
操作时间	1 hr 20 min
测试时间	4 hr 45 min
Homogenous (no wash)	No
批间变异系数（CV）	<12%
批内变异系数（CV）	<10%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	5 x 96 Tests
组份	- 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	IL-17A
物种（Tested）	羊
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin
Gene aliases	IL-17a
Gene ID	(Sheep) 101103931
Gene symbol	IL17A

Ovine IL-17A quantitates ovine IL-17A in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant ovine IL-17A.绵羊IL-17A定量检测血清，血浆，上清液中的绵羊IL-17A。该检测试剂盒将只识别天然和重组绵羊IL-17A。Target information 靶标信息Interleukin-17A (IL-17A, CTLA-8) is a CD4+ T cell-derived cytokine that promotes inflammatory responses in cell lines and is elevated in rheumatoid arthritis, asthma, multiple sclerosis, psoriasis, and transplant rejection. IL-17A is a 32 kDa long, disulfide-linked homodimer consisting of 136 amino acids that is a member of a six-species family of proteins (IL-17A-17F) and signals through the IL-17 receptor (IL-17R/CDw217). High levels of IL-17A homodimer are produced by activated peripheral blood CD4+ T-cells, and IL-17A also enhances expression of the intracellular adhesion molecule-1 (ICAM-1) in human fibroblasts. In particular, human IL-17A also stimulates epithelial, endothelial, or fibroblastic cells to secrete IL-6, IL-8, G-CSF, and PGE2. In the presence of human IL-17A, fibroblasts can sustain the proliferation of CD34+ hematopoietic progenitors and induce maturation into neutrophils. Mouse, rat, and human IL-17A can induce IL-6 secretion in mouse stromal cells, indicating that all homologs can recognize the mouse receptor. IL-17A regulates the activities of NF-kappa B and mitogen-activated protein kinases, stimulates the expression of IL-6 and cyclooxygenase-2 (PTGS2/COX-2), and enhances the production of nitric oxide (NO).白介素-17A（IL-17A，CTLA-8）是CD4 + T细胞衍生的细胞因子，可促进细胞系中的炎症反应，并在类风湿性关节炎，哮喘，多发性硬化症，牛皮癣和移植排斥反应中升高。 IL-17A是一个32 kDa长的二硫键连接的同型二聚体，由136个氨基酸组成，是六种蛋白质家族（IL-17A-17F）的成员，并通过IL-17受体（IL-17R / CDw217）。活化的外周血CD4 + T细胞产生高水平的IL-17A同型二聚体，并且IL-17A还增强人成纤维细胞中细胞内粘附分子1（ICAM-1）的表达。特别地，人IL-17A还刺激上皮，内皮或成纤维细胞分泌IL-6，IL-8，G-CSF和PGE2。在人IL-17A存在的情况下，成纤维细胞可以维持CD34 +造血祖细胞的增殖并诱导成熟为嗜中性粒细胞。小鼠，大鼠和人IL-17A可以诱导小鼠基质细胞分泌IL-6，这表明所有同源物都可以识别小鼠受体。 IL-17A调节NF-κB和丝裂原激活的蛋白激酶的活性，刺激IL-6和环氧合酶2（PTGS2 / COX-2）的表达，并增强一氧化氮（NO）的产生。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

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Ovine IL-17A ELISA Kit ELISA试剂盒,Ovine IL-17A ELISA Kit/绵羊IL-17A ELISA试剂盒

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