Mouse Clusterin ELISA Kit ELISA试剂盒,Mouse Clusterin ELISA /小鼠Clusterin ELISA试剂盒-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Mouse Clusterin ELISA Kit ELISA试剂盒,Mouse Clusterin ELISA /小鼠Clusterin ELISA试剂盒

2024-10-24

Mouse Clusterin ELISA /小鼠Clusterin ELISA试剂盒

货号：EM18RB,EM18RBX5,EM18RBX10

规格：96 Tests,5X96 Tests,10X96 tests

价格：6641,29884,57271

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：小鼠

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	0.1 ng/mL
检测范围	0.1-24 ng/mL
样本类型/体积	血清 50 μL 血浆 50 μL 上清液 50 μL
操作时间	1 hr 20 min
测试时间	4 hr 45 min
Homogenous (no wash)	No
批间变异系数（CV）	<12%
批内变异系数（CV）	<10%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	5 x 96 Tests
组份	- 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	Apolipoprotein J
Protein aliases	Apo-J, Apolipoprotein J, Clusterin, Clusterin alpha chain, Clusterin beta chain, Clustrin, complement lysis inhibitor, SGP-2, Sulfated glycoprotein 2, testosterone repressed prostate message, testosterone repressed prostate message-2
物种（Tested）	小鼠
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin
Gene aliases	AI893575, ApoJ, Cli, Clu, D14Ucla3, Msgp-2, Sgp-2, Sgp2, SP-40, Sugp-2
Gene ID	(Mouse) 12759
Gene symbol	Clu
UniProt ID	(Mouse) Q06890

Mouse Clusterin quantitates mouse Clusterin in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse Clusterin.小鼠Clusterin定量分析血清，血浆，上清液中的小鼠Clusterin。该检测试剂盒将专门识别天然和重组小鼠Clusterin。Target information 靶标信息Isoform 1 functions as extracellular chaperone that prevents aggregation of nonnative proteins. Prevents stress-induced aggregation of blood plasma proteins. Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro). Does not require ATP. Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70. Does not refold proteins by itself. Binding to cell surface receptors triggers internalization of the chaperone-client complex and subsequent lysosomal or proteasomal degradation. Secreted isoform 1 protects cells against apoptosis and against cytolysis by complement. Intracellular isoforms interact with ubiquitin and SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes and promote the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes proteasomal degradation of COMMD1 and IKBKB. Modulates NF-kappa-B transcriptional activity. Nuclear isoforms promote apoptosis. Mitochondrial isoforms suppress BAX-dependent release of cytochrome c into the cytoplasm and inhibit apoptosis. Plays a role in the regulation of cell proliferation.Isoform 1充当防止非天然蛋白聚集的细胞外分子伴侣。防止压力诱导的血浆蛋白聚集。抑制APP，APOC2，B2M，CALCA，CSN3，SNCA和易聚集的LYZ变体（体外）形成淀粉样蛋白原纤维。不需要ATP。将部分未折叠的蛋白质保持在适合随后被其他伴侣（例如HSPA8 / HSC70）重折叠的状态。自身不折叠蛋白质。与细胞表面受体的结合触发伴侣-客户复合物的内在化和随后的溶酶体或蛋白酶体降解。分泌的同工型1通过补体保护细胞免于凋亡和细胞溶解。细胞内同工型与遍在蛋白和SCF（SKP1-CUL1-F-box蛋白）E3遍在蛋白-蛋白连接酶复合物相互作用，并促进遍在蛋白化和随后蛋白酶体降解靶蛋白。促进COMMD1和IKBKB的蛋白酶体降解。调节NF-κB的转录活性。核亚型促进细胞凋亡。线粒体同工型抑制BAX依赖的细胞色素c释放到细胞质中并抑制细胞凋亡。在细胞增殖的调节中起作用。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

技术参数

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Mouse Clusterin ELISA Kit ELISA试剂盒,Mouse Clusterin ELISA /小鼠Clusterin ELISA试剂盒

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