Mouse VEGFR3 ELISA Kit ELISA试剂盒,Mouse VEGFR3 ELISA Kit/小鼠VEGFR3 ELISA试剂盒

2024-10-24

Mouse VEGFR3 ELISA Kit/小鼠VEGFR3 ELISA试剂盒

货号:EM73RB,EM73RBX5,EM73RBX10

规格:96 Tests,5X96 Tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:小鼠

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.2 ng/mL

检测范围0.2-50 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameVEGF Receptor 3
Protein aliaseschylous ascites, FLT-4, Fms-like tyrosine kinase 4, receptor protein tyrosine kinase, Tyrosine-protein kinase receptor FLT4, Vascular endothelial growth factor receptor 3, vascular endothelial growth factor receptor-3, VEGFR-3

物种(Tested)

小鼠

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesAI323512, Chy, Flt-4, Flt4, VEGFR-3, VEGFR3
Gene ID(Mouse) 14257
Gene symbolFlt4
UniProt ID(Mouse) P35917
Mouse VEGFR3 quantitates mouse VEGFR3 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse VEGFR3.小鼠VEGFR3定量检测血清,血浆,上清液中的小鼠VEGFR3。 该检测试剂盒将专门识别天然和重组小鼠VEGFR3。Target information 靶标信息Vascular endothelial growth factor is a key regulator of blood vessel development in embryos and angiogenesis in adult tissues. Unlike VEGF, the related VEGFC stimulates the growth of lymphatic vessels through its specificl ymphatic endothelial receptor VEGFR-3. In 1998, Dumont showed that targeted inactivation of the VEGFR-3 gene in mice resulted in defective blood vessel development in early embryos. Vasculogenesis and angiogenesis occurred, but large vessels became abnormally organized with defective lumens, leading to fluid accumulation in the pericardial cavity and cardiovascular failure at embryonic day 9.5. Thus, VEGFR3 has an essential role in the development of theembryonic cardiovascular system before the emergence of the lymphatic vessels.血管内皮生长因子是胚胎中血管发育和成人组织中血管生成的关键调节剂。 与VEGF不同,相关的VEGFC通过其特异性的淋巴管内皮受体VEGFR-3刺激淋巴管的生长。 1998年,Dumont发现小鼠中VEGFR-3基因的靶向失活导致早期胚胎中的血管发育缺陷。 发生血管生成和血管生成,但是大血管变得异常组织,内腔缺损,导致在胚胎第9.5天液体积聚在心包腔中并导致心血管衰竭。 因此,VEGFR3在淋巴管出现之前在胚性心血管系统的发育中具有重要作用。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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