Rabbit Leptin ELISA Kit ELISA试剂盒,Rabbit Leptin ELISA Kit/兔瘦蛋白ELISA试剂盒

2024-10-24

Rabbit Leptin ELISA Kit/兔瘦蛋白ELISA试剂盒

货号:ER11RB,ER11RBX5

规格:96 Tests,5X96 Tests

价格:6641,29884

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:兔

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.2 ng/mL

检测范围0.2-50 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameLeptin
Protein aliasesleptin

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesOB
Gene ID(Rabbit) 100008747
Gene symbolLEP
Rabbit Leptin quantitates rabbit Leptin in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rabbit Leptin.兔瘦素定量测定血清,血浆,上清液中的兔瘦素。该检测试剂盒将专门识别天然和重组兔瘦素。Target information 靶标信息Leptin is a 167 amino acid long protein hormone with important effects in regulating body weight, metabolism and reproductive function. Leptin is approximately 16 kDa in mass and encoded by the obese (ob) gene. Leptin is expressed predominantly by adipocytes, which fits with the idea that body weight is sensed as the total mass of fat in the body. Smaller amounts of leptin are also secreted by cells in the epithelium of the stomach and in the placenta. Leptin receptors are highly expressed in areas of the hypothalamus known to be important in regulating body weight, as well as in T lymphocytes and vascular endothelial cells. Leptin's effects on body weight are mediated through effects on hypothalamic centers that control feeding behavior and hunger, body temperature and energy expenditure. Leptin is involved in regulating food intake, energy expenditure, and adiposity through hypothalamic leptin receptors. Leptin promotes hematopoiesis, angiogenesis, wound healing, inflammation, immune responses, influences pubertal development and fetal growth. Studies have investigated the role of leptin in obesity, anorexia nervosa, insulin resistance, and hypertension. Leptin also has thermogenic actions and regulates enzymes of fatty acid oxidation. Severe hereditary obesity in rodents and humans can be caused by defects in leptin production.瘦素是一种167个氨基酸的长蛋白激素,在调节体重,代谢和生殖功能方面具有重要作用。瘦蛋白的质量约为16 kDa,由肥胖(ob)基因编码。瘦素主要由脂肪细胞表达,这与将体重视为体内脂肪的总质量的想法相吻合。胃上皮细胞和胎盘中的细胞也会分泌少量的瘦素。瘦素受体在下丘脑的区域中高表达,已知在调节体重方面很重要,以及在T淋巴细胞和血管内皮细胞中。瘦素对体重的影响通过对下丘脑中枢的影响来介导,该下丘脑中枢控制进食行为和饥饿,体温和能量消耗。瘦素通过下丘脑瘦素受体参与调节食物摄入,能量消耗和肥胖。瘦素促进造血,血管生成,伤口愈合,炎症,免疫反应,影响青春期发育和胎儿生长。研究已经研究了瘦素在肥胖,神经性厌食症,胰岛素抵抗和高血压中的作用。瘦素还具有生热作用并调节脂肪酸氧化酶。瘦蛋白生产中的缺陷可能导致啮齿动物和人类中的严重遗传性肥胖。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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