Mouse IL-2 R alpha ELISA Kit ELISA试剂盒,Mouse IL-2 R alpha ELISA Kit/小鼠IL-2 R alpha ELISA试剂盒

2024-10-24

Mouse IL-2 R alpha ELISA Kit/小鼠IL-2 R alpha ELISA试剂盒

货号:EM44RB,EM44RBX5,EM44RBX10

规格:96 Tests,5X96 Tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:小鼠

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

10 pg/mL

检测范围10-2,500 pg/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameCD25
Protein aliasesCD25, IL-2 receptor subunit alpha, IL-2-RA, IL-2R alpha chain, IL-2R subunit alpha, IL2-RA, Interleukin-2 receptor subunit alpha, p55, p55 chain

物种(Tested)

小鼠

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesCD25, Il2r, Il2ra, Ly-43
Gene ID(Mouse) 16184
Gene symbolIl2ra
UniProt ID(Mouse) P01590
Mouse IL-2 R alpha quantitates mouse IL-2 R alpha in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse IL-2 R alpha.小鼠IL-2 R alpha定量检测血清,血浆,上清液中的小鼠IL-2 R alpha。该检测试剂盒将专门识别天然和重组小鼠IL-2 Rα。Target information 靶标信息CD25 (IL2 receptor alpha chain/IL2RA) is a cytokine that plays a role in the proliferation of T and B lymphocytes. The receptor of this cytokine (IL2RA) is a heterotrimeric protein complex with a gamma chain also shared by interleukin 4 (IL4) and interleukin 7 (IL7). IL2RA, IL2R beta chain (IL2RB), and the IL2R gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric IL2RA chains result in low-affinity receptor, while homodimeric IL2RB chains produce a medium-affinity receptor. The expression of IL2 in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. IL2 is primarily produced by mature T cells. IL2 plays an important role as a growth factor, differentiation factor, and regulator of cell death. IL-2 stimulates the proliferation of B cells, augments natural killer cell activity, and inhibits granulocyte macrophage colony formation. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests a role in the immune response to antigenic stimuli. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.CD25(IL2受体α链/ IL2RA)是一种细胞因子,在T和B淋巴细胞的增殖中起作用。该细胞因子的受体(IL2RA)是异源三聚体蛋白复合物,具有由白介素4(IL4)和白介素7(IL7)共享的γ链。 IL2RA,IL2Rβ链(IL2RB)和IL2Rγ链(IL2RG)构成了高亲和力的IL2受体。同型二聚体IL2RA链产生低亲和力受体,同型二聚体IL2RB链产生中等亲和力受体。 IL2在成熟胸腺细胞中的表达是单等位基因,代表了控制单个基因精确表达的异常调节模式。 IL2主要由成熟的T细胞产生。 IL2作为生长因子,分化因子和细胞死亡调节剂起着重要作用。 IL-2刺激B细胞的增殖,增强自然杀伤细胞的活性,并抑制粒细胞巨噬细胞集落的形成。小鼠中类似基因的定向破坏会导致溃疡性结肠炎样疾病,这提示其在对抗原刺激的免疫反应中起作用。该基因的突变与白细胞介素2受体α缺乏有关。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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