FeraSpin R/肝脏显像MRI 造影剂 130-095-138 MB ,FeraSpin R/肝脏核磁共振成像(MRI )MRI 造影剂

2024-10-24

FeraSpin R/肝脏核磁共振成像(MRI )MRI 造影剂

货号:130-095-138 ,130-095-139

规格:for 5 injections,for 5×5 injections

价格:5348,25403

产品类型:小动物造影剂

品牌:Miltenyi

FeraSpin R is a nanoparticulate superparamagnetic iron oxide contrast agent specifically formulated for pre-clinical magnetic resonance imaging (MRI).It is a contrast agent of high relaxivity enhancing the contrast in T2- and T2*-weighted MRI due to a shortening of the spin-spin relaxation time (T2).Upon intravenous injection, FeraSpin R is rapidly taken up by the Kupffer cells (macrophages of the liver) resulting in a short blood half-life of a few minutes. FeraSpin R accumulates particularly in the liver and spleen and is degraded with its iron being transferred into the physiological iron stores.FeraSpin R是一种超顺磁化氧化铁纳米微粒造影剂,专门用于临床前磁共振成像(MRI)。其平均颗粒大小较大,粒径分布较广泛,因此易被肝脏及脾脏中的巨噬细胞所摄入。它是一种高松弛度的造影剂,由于缩短了spin-spin relaxation time (T2)时间,增强了T2-和T2*-weightedMRI的对比度。静脉注射后,FeraSinR被Kupffer细胞(肝脏的巨噬细胞)迅速吸收,导致血液半衰期短几分钟。 Fera SpinR在肝脏和脾脏中积累,并随着其铁被转移到生理铁库中而降解。

优点:

-涵盖全面,应用范围广;- 操作简单; - 高效。

数据:

图1.FeraSpin R 纳米磁珠的结构公式

组成成分:

▪850 µL FeraSpin™ R, MRI contrast agent (superparamagnetic iron oxide [SPIO] nanoparticles) or 5×850 µL FeraSpin™ R, MRI contrast agent (superparamagnetic iron oxide [SPIO] nanoparticles).

相关产品:

▪ExiTron V二聚化非离子胞外CT造影剂(货号#130-095-283)▪ExiTron P CT 肾排泄血管造影剂(货号#130-095-144)▪ExiTron nano 6000 肝脏显像CT 造影剂(货号#130-095-146)▪ExiTron nano 12000CT 血管造影剂(货号#130-095-698)▪GadoSpin F动脉粥样硬化成像剂MRI 造影剂(货号#130-095-162)▪GadoSpin P MR 血管造影剂(货号#130-095-136)▪GadoSpin D动态造影增强MRI 造影剂(货号#130-095-164)▪GadoSpin M 胞外MRI 造影剂(货号#130-095-134)▪FeraSpin R 肝脏显像MRI 造影剂(货号#130-095-138)▪FeraSpin XS 纳米微粒血管MRI 造影剂(货号#130-095-140)▪FeraSpin S 纳米微粒(货号#130-095-166)▪FeraSpin M纳米微粒血管MRI 造影剂(货号#130-095-168)▪FeraSpinL纳米微粒血管MRI 造影剂(货号#130-095-170)▪PolySon H超声微泡(货号#130-095-152)▪PolySon L hard-shell 超声微泡(货号#130-095-150)▪NiraWave C 光学显像造影剂(货号#130-095-154)▪NiraWave M 光学炎症显像造影剂(货号#130-095-157)▪NiraWave nano 780 光学血管造影剂(货号#130-095-693)
参考文献
1. Lawaczeck, R. et al. (1997) Magnetic iron oxide particles coated with carboxydextran for parenteral administration and liver contrasting. Pre-clinical profile of SH U555A. Acta Radiol. 38: 584-5972. Murakami, T. et al. (2001) Evaluation of regional liver damage by magnetic resonance imaging with superparamagnetic iron oxide in rat liver. Dig. Dis. Sci. 46: 148-155

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