130-095-152 PolySon H超声微泡 MB ,PolySon H超声微泡

2024-10-24

PolySon H超声微泡

货号:130-095-152,130-095-153

规格:for 5 injections,for 5×5 injections

价格:0,0

产品类型:小动物造影剂

品牌:Miltenyi

PolySon™ H and PolySon™ L consist of micrometer-sized air-filled polymeric particles specifically formulated for pre-clinical ultrasound imaging.Due to large differences in their density and compressibility compared to tissue or plasma, dispersed PolySon microbubbles are highly echogenic.Upon intravenous injection, the intact microbubbles circulate in the blood pool for up to 10 minutes and are taken up by the reticuloendothelial system (RES), particularly in the liver and spleen.ApplicationsPolySon can be applied in various ultrasound imaging techniques, such as harmonic, subharmonic and B-mode imaging.Moreover, it is particularly suited for stimulated acoustic emission (SAE) imaging (bubble rupture) using a relativelylow-energy ultrasound beam (low mechanical index – PolySon L) or using a relatively high-energy ultrasound beam (high mechanical index – PolySon H).PolySon is indicated for use in ultrasound imaging of small animals, for example mice, to facilitate evaluation of perfusion patterns and visualization of the liver and spleen.Examples include sensitive particle acoustic quantification (SPAQ) studies, imaging of liver tumors and perfusion studies of the cardiovascular system, renal system, or intratumoral vessels.PolySon™ H and PolySon™ L由微米大小的充气聚合物粒子组成,专门用于临床前超声成像。由于它们的密度和压缩性与组织或血浆有很大的差异,分散的PolySon微泡具有很高的回声性。静脉注射时,完整的微泡在血池中循环高达10分钟,并被网状内皮系统(RES)吸收,特别是在肝脏和脾脏部位。静脉注射时,完整的微泡在血池中循环高达10分钟,并被网状内皮系统(RES)吸收,特别是在肝脏和脾脏部位。应用PolySon可应用于各种超声成像技术,如harmonic, subharmonic he B-mode成像。此外,它特别适用于使用相对低能超声束(低机械指数-Polyson L)或使用相对高能超声束(高机械指数-Polyson H)的受激声发射(SAE)成像(气泡破裂)。PolySon被用于小动物的超声成像,例如小鼠,以方便评估灌注模式和肝脏和脾脏的可视化。例子包括敏感粒子声学定量(Spaq)研究,肝脏肿瘤的成像和心血管系统、肾脏系统或瘤内血管的灌注研究。

优点:

-涵盖全面,应用范围广;- 操作简单; - 高效。

数据:

图1.聚合物微泡的示意图

组成成分:

▪50 mg PolySon™ H, ultrasound contrast agent (polymeric microbubbles) or 5×50 mg PolySon™ H, ultrasound contrast agent (polymeric microbubbles).

相关产品:

▪ExiTron V二聚化非离子胞外CT造影剂(货号#130-095-283)▪ExiTron P CT 肾排泄血管造影剂(货号#130-095-144)▪ExiTron nano 6000 肝脏显像CT 造影剂(货号#130-095-146)▪ExiTron nano 12000CT 血管造影剂(货号#130-095-698)▪GadoSpin F动脉粥样硬化成像剂MRI 造影剂(货号#130-095-162)▪GadoSpin P MR 血管造影剂(货号#130-095-136)▪GadoSpin D动态造影增强MRI 造影剂(货号#130-095-164)▪GadoSpin M 胞外MRI 造影剂(货号#130-095-134)▪FeraSpin R 肝脏显像MRI 造影剂(货号#130-095-138)▪FeraSpin XS 纳米微粒血管MRI 造影剂(货号#130-095-140)▪FeraSpin S 纳米微粒(货号#130-095-166)▪FeraSpin M纳米微粒血管MRI 造影剂(货号#130-095-168)▪FeraSpinL纳米微粒血管MRI 造影剂(货号#130-095-170)▪PolySon H超声微泡(货号#130-095-152)▪PolySon L hard-shell 超声微泡(货号#130-095-150)▪NiraWave C 光学显像造影剂(货号#130-095-154)▪NiraWave M 光学炎症显像造影剂(货号#130-095-157)▪NiraWave nano 780 光学血管造影剂(货号#130-095-693)
参考文献
1. Reinhardt, M. et al. (2005) Sensitive particle acoustic quantification (SPAQ): a new ultrasound-based approach for the quantification of ultrasound contrast media in high concentrations. Invest. Radiol. 40: 2-72. Tiemann, K. et al. (2000) Stimulated acoustic emission: pseudo-Doppler shifts seen during the destruction of nonmoving microbubbles. Ultrasound Med. Biol. 26: 1161-11673. Hauff, P. et al. (2004) Molecular targeting of lymph nodes with L-selectin ligand-specific US contrast agent: a feasibility study in mice and dogs. J. Immunother. 231: 667-673

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