Collagen IV Polyclonal Antibody/胶原IV多克隆抗体

货号：PA1-28534

规格：100 µg

价格：6553

产品类型：免疫组化一抗

品牌：Thermo Fisher

抗原：Collagen Type IV from human and bovine placenta

物种：其它

宿主：兔

抗体亚型：IgG

荧光染料：其它

类型:	多抗	同型对照：
浓度：	1 mg/mL	用法：	1:5000-1:50000(ELISA)；1:50-1:200(IHC (P))；1:100(IP)；1:1,000-1:10,000(WB)

产品详细信息Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.靶标信息Collagen IV is a major constituent of the basement membranes along with laminins and enactins. Collagen IV is composed of alpha 1 IV chain and alpha 2 IV chain in 2:1 ratio. Collagen IV can form insoluble fibers with high tensile strength. Antibody to collagen IV is useful in detecting the loss of parts of basement membrane in carcinomas.仅用于科研。不用于诊断过程。未经明确授权不得转售。

数据

Collagen IV Antibody (PA1-28534) in IHC (P)Immunohistochemistry analysis of Collagen IV was performed in human kidney, glomeruli and liver tissues using Collagen IV Polyclonal Antibody (Product # PA1-28534) at a dilution of 1:400 for 45 minutes a room temperature. The antibody showed strong staining in FFPE sections of human kidney (Left) with strong red staining observed in glomeruli and liver (Right) with strong staining in sinusoids. Staining for both tissues was consistent with a basement membrane distribution. Slides were steamed in 0.01 M sodium citrate buffer, pH 6.0 at 99-100°C - 20 minutes for antigen retrieval. Collagen IV Antibody (PA1-28534)Journal of immunology research 2018 -Figure 12 TCP 100x collagen IV stain showing moderate fibrosis.

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参考文献：

1.Journal of immunology researchInflammatory-Driven Angiogenesis in Bone Augmentation with Bovine Hydroxyapatite, B-Tricalcium Phosphate, and Bioglasses: A Comparative Study.

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