CD36 Monoclonal Antibody (HM36), PE, eBioscience
货号:12-0362-82
规格:100 µg
市场价格:850
产品类型:流式抗体
品牌:eBioscience
抗原:CD36
物种:小鼠
宿主:Armenian hamster仓鼠
抗体亚型:IgG
克隆号:HM36
荧光染料:PE
类型: | 流式抗体 | 同型对照: | Armenian Hamster IgG Isotype Control (eBio299Arm), PE, eBioscience |
浓度: | 0.2 mg/mL | 用法: | 0.5 μg/test(Flow) |
产品详细信息Description:
This HM36 antibody recognizes mouse CD36, also known as scavenger receptor BIII.Applications Reported: This HM36 antibody has been reported for use in flow cytometric analysis.Applications Tested: This HM36 antibody has been tested by flow cytometric analysis of thioglycolate-elicited peritoneal macrophages. This may be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser
靶标信息
CD36 (fatty acid translocase, FAT) is an 88 kDa, ditopic glycosylated protein that belongs to the class B family of scavenger receptors. CD36 is expressed by most resting marginal zone B cells but not by follicular and B1 B cells, and is rapidly induced on Follicular B cells in vitro upon TLR and CD40 stimulation. CD36 does not affect the development of B cells, but modulates both primary and secondary antibody response. Similar to glucose transporter GLUT4, CD36 is translocated from intracellular pools to the plasma membrane following cell stimulation by insulin. In mouse, CD36 is responsible for gustatory perception of long-chain fatty acids. CD36 is preferentially found within lipid rafts, which facilitates its association with receptors, signaling and adapter molecules. CD36 binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. Further, CD36 may function as a cell adhesion molecule and directly mediates cyto-adherence of Plasmodium falciparum parasitized erythrocytes. Mutations in the CD36 gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants encoding the CD36 protein have been found.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
数据 |
CD36 Antibody (12-0362-82) in FlowBALB/c mouse thioglycolate-elicited peritoneal exudate cells were stained with F4/80 Monoclonal Antibody, FITC (Product # 11-4801-82) and 0.25 µg of Armenian Hamster IgG Isotype Control, PE (Product # 12-4888-81) (left) or 0.25 µg of CD36 Monoclonal Antibody, PE (right). |
推荐产品: |
二抗荧光二抗免疫组化一抗标签抗体 |
©
bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪是专业的授权总代理区域代理经销平台。
© 如需询价,请加客服QQ:1749072012 、客服微信:jinshanbio,或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务,数据资源基于CC协议。
© 本文地址:
https://gibcohyclone.cn/thread-48959.htm
特别声明:以上内容(如有图片亦包括在内)来源于授权厂家或网络,如有侵权,请联系删除,本平台不提供信息存储服务。
Notice: The content above (including the pictures if any)comes from authorized manufacturers or networks. In case of infringement, please contact to delete it. This platform does not provide information storage services.