Rabbit anti Human EWSR1 antibody 伯乐人 VPA00863 EWSR1 抗体

2024-10-28

Rabbit anti Human EWSR1 antibody

货号:VPA00863

规格:100 µl

市场价格:3171

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:EWSR1

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti Human EWSR1 antibodyrecognizes EWSR1, also known as EWS RNA-binding protein variant 1.This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11;22)(q24;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14 (provided by RefSeq, Jul 2009).Rabbit anti Human EWSR1 antibody detects a band of 85 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationRabbit polyclonal antibody purified by affinity chromatography on immunogen
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.09% Sodium Azide2% Sucrose
ImmunogenSynthetic peptide corresponding to the N terminal region of human EWSR1
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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技术参数

产品应用 WB

产品类型 多克隆抗体

推荐用于 WB

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