Rabbit anti Human plectin antibody VPA00847 伯乐人 plectin抗体 WB-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rabbit anti Human plectin antibody VPA00847 伯乐人 plectin抗体 WB

2024-10-28

Rabbit anti Human plectin antibody

货号：VPA00847

规格：100 µl

市场价格：2890

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：plectin

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti Human plectin antibodyrecognizes plectin, also known as hemidesmosomal protein 1, plectin 1, PCN and intermediate filament binding protein 500 kDa.Plectin is a prominent member of an important family of structurally termed plakins or cytolinkers that are capable of interlinking different elements of the cytoskeleton. Plakins, with their multi-domain structure and enormous size, not only play crucial roles in maintaining cell and tissue integrity and orchestrating dynamic changes in cytoarchitecture and cell shape, but also serve as scaffolding platforms for the assembly, positioning, and regulation of signaling complexes. Plectin is expressed as several protein isoforms in a wide range of cell types and tissues from a single gene located on chromosome 8 in humans. Expression of specific plectin isoforms were found to be dependent on cell type and stage of development. A number of groups reported that patients suffering from epidermolysis bullosa simplex with muscular dystrophy (EBS-MD) lacked plectin expression in skin and muscle tissues due to defects in the plectin gene . Two other subtypes of plectin-related EBS have been described: EBS-pyloric atresia (PA) and EBS-Ogna (provided by RefSeq, Aug 2011).Rabbit anti Human plectin antibody detect bands of 300-500 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Rabbit polyclonal antibody purified by affinity chromatography on immunogen
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	0.09% Sodium Azide
Immunogen	Recombinant protien of human plectin
Acknowledgements	PrecisionAb is a trademark of Bio-Rad Laboratories
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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技术参数

产品应用 WB

产品类型多克隆抗体

推荐用于 WB

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Rabbit anti Human plectin antibody VPA00847 伯乐 人 plectin抗体 WB

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Rabbit anti Human plectin antibody VPA00847 伯乐人 plectin抗体 WB