Rabbit anti Human ROCK1 antibody 伯乐 ROCK1 抗体 人 VPA00923

2024-10-28

Rabbit anti Human ROCK1 antibody

货号:VPA00923

规格:100 µl

市场价格:2746

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:ROCK1

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti Human ROCK1 antibodyrecognizes ROCK1, also known as P160ROCK and rho-associated protein kinase 1.This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. A pseudogene, related to this gene, is also located on chromosome 18 (provided by RefSeq, Aug 2015).Rabbit anti Human ROCK1 antibody detects a band of 160 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationRabbit polyclonal antibody purified by affinity chromatography on immunogen
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.09% Sodium Azide<50% Glycerol
ImmunogenRecombinant protein of human ROCK1
Approx. Protein ConcentrationsIgG concentration 0.5 mg/ml
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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技术参数

产品应用 WB; IP

产品类型 多克隆抗体

推荐用于 WB; IP

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