Rabbit anti Human CDK4 antibody 伯乐 VPA00749 CDK4抗体-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rabbit anti Human CDK4 antibody 伯乐 VPA00749 CDK4抗体

2024-10-28

Rabbit anti Human CDK4 antibody

货号：VPA00749

规格：100 µL

市场价格：3171

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：CDK4

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti Human CDK4 antibodyrecognizes cyclin-dependent kinase 4, also known as cell division protein kinase 4.The protein encoded by CDK4 is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products ofS. cerevisiaecdc28 andS. pombecdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in CDK4 as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of CDK4 have been reported (provided by RefSeq, Jul 2008).Rabbit anti Human CDK4 antibody detects a band of 30 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Rabbit polyclonal antibody purified by affinity chromatography on immunogen.
Buffer Solution	Phosphate buffered saline.
Preservative Stabilisers	0.09% Sodium Azide (NaN3)2% Sucrose
Immunogen	Synthetic peptide encompassing the center region of human CDK4
Approx. Protein Concentrations	IgG concentration 0.5 mg/ml.
Acknowledgements	PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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技术参数

产品应用 WB

产品类型 PrecisionAb Polyclonal

推荐用于 WB

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Rabbit anti Human CDK4 antibody 伯乐 VPA00749 CDK4抗体

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