Rabbit anti Human calpain-10 antibody 伯乐 calpain-10抗体 人VPA00912

2024-10-28

Rabbit anti Human calpain-10 antibody

货号:VPA00912

规格:100 µl

市场价格:2746

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原: calpain-10

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti Human calpain-10 antibodyrecognizes calpain-10, also known as calcium-activated neutral proteinase 10 and calpain-like protease CAPN10.The calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation; domain II, the protease domain; domain III, a linker domain of unknown function; and domain IV, the calmodulin-like calcium-binding domain. CAPN10 encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. CAPN10 is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for CAPN10 (provided by RefSeq, Sep 2010).Rabbit anti Human calpain-10 antibody detects bands of 58 and 75 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationRabbit polyclonal antibody purified by affinity chromatography on immunogen
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.09% Sodium Azide<50% Glycerol
ImmunogenRecombinant protein of human calpain-10
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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技术参数

产品应用 WB

产品类型 多克隆抗体

推荐用于 WB

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