Rabbit anti Human C antibody 伯乐 GSTM1 抗体 人VPA00874

2024-10-28

Rabbit anti Human C antibody

货号:VPA00874

规格:100 µl

市场价格:2890

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:Rabbit anti Human GSTM1 antibody

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti Human GSTM1 antibodyrecognizes the glutathione S-transferase Mu 1, also known as GST HB subunit 4, GST class-mu 1, S-(hydroxyalkyl)glutathione lyase and glutathione S-alkyltransferase.Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. GSTM1 encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of GSTM1 (provided by RefSeq, Jul 2008).Rabbit anti Human GSTM1 antibody detects a band of 25 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationRabbit polyclonal antibody purified by affinity chromatography on immunogen
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.09% Sodium Azide2% Sucrose
ImmunogenRecombinant protein of human GSTM1
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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技术参数

产品应用 WB

产品类型 多克隆抗体

推荐用于 WB

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