Rabbit anti Human transcription factor E2F2 antibody 伯乐 VPA00579 transcription factor E2F2抗体

2024-10-28

Rabbit anti Human transcription factor E2F2 antibody

货号:VPA00579

规格:100 µL

市场价格:2890

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:transcription factor E2F2

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti Human transcription factor E2F2 antibodyrecognizes the transcription factor E2F2.The protein encoded by the E2F2 gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. E2F2 binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits overall 46% amino acid identity to E2F1 (provided by RefSeq, Jul 2008).Rabbit anti Human E2F2 antibody detects a band of 47 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationRabbit polyclonal antibody purified by affinity chromatography.
Buffer SolutionPhosphate buffered saline.
Preservative Stabilisers0.09% Sodium Azide2% Sucrose
ImmunogenSynthetic peptide directed towards the middle region of human transcription factor E2F2
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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技术参数

产品应用 WB

产品类型 PrecisionAb Polyclonal

推荐用于 WB

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