Rabbit anti Human PCBP2 antibody 伯乐人 PCBP2抗体 VPA00661-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rabbit anti Human PCBP2 antibody 伯乐人 PCBP2抗体 VPA00661

2024-10-28

Rabbit anti Human PCBP2 antibody

货号：VPA00661

规格：100 µl

市场价格：3613

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：PCBP2

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti Human PCBP2 antibodyrecognizes the poly(rC)-binding protein 2, also known as alpha-CP2, heterogenous nuclear ribonucleoprotein (hnRNP) E2.The protein encoded by PCBP2 gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. PCBP2 and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for PCBP2 (provided by RefSeq, Jul 2008).Rabbit anti Human PCBP2 antibody detects a band of 39 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Rabbit polyclonal antibody purified by affinity chromatography on Protein A.
Buffer Solution	Phosphate buffered saline.
Preservative Stabilisers	0.09% Sodium Azide2% Sucrose
Immunogen	Synthetic peptide encompassing part of the middle region of human PCBP2
Acknowledgements	PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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技术参数

产品应用 WB

产品类型多克隆抗体

推荐用于 WB

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Rabbit anti Human PCBP2 antibody 伯乐人 PCBP2抗体 VPA00661

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