Rabbit anti Human topoisomerase II alpha antibody 伯乐 VPA00604 人 WB Topoisomerase II Alpha antibody-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rabbit anti Human topoisomerase II alpha antibody 伯乐 VPA00604 人 WB Topoisomerase II Alpha antibody

2024-10-28

Rabbit anti Human topoisomerase II alpha antibody

货号：VPA00604

规格：100 µl

市场价格：2890

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：topoisomerase II alpha

物种：人/小鼠

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti Human topoisomerase II alpha antibodyrecognizes the DNA topoisomerase II alpha, also known as DNA gyrase or DNA topoisomerase (ATP-hydrolyzing).TOP2A gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromosome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in TOP2A have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia (provided by RefSeq, Jul 2010).Rabbit anti Human topoisomerase II alpha antibody detects a band of 190 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution	Phosphate buffered saline.
Preservative Stabilisers	0.09% Sodium Azide2% Sucrose
Immunogen	Synthetic peptide directed towards the C terminal region of human topoisomerase II alpha
Approx. Protein Concentrations	IgG concentration 0.5 mg/ml.
Acknowledgements	PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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技术参数

产品应用 wb

产品类型多克隆抗体

推荐用于 wb

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Rabbit anti Human topoisomerase II alpha antibody 伯乐 VPA00604 人 WB Topoisomerase II Alpha antibody

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