Rabbit anti Human CREB binding protein antibody 伯乐 VPA00303 CREB binding protein抗体-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rabbit anti Human CREB binding protein antibody 伯乐 VPA00303 CREB binding protein抗体

2024-10-28

Rabbit anti Human CREB binding protein antibody

货号：VPA00303

规格：100 uL

市场价格：2890

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：CREB binding protein

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti Human CREB binding protein antibodyrecognizes CREB binding protein, also known as CREBBP and CBP.CREB binding protein is ubiquitously expressed and is involved in the transcriptional co-activation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), CREB binding protein is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by the CREB binding protein gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in the CREB binding protein gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations involving the CREB binding protein gene have been associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants encoding different isoforms (provided by RefSeq, Feb 2009).Rabbit anti Human CREB binding protein antibody detects a band of 300 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution	Phosphate buffered saline.
Preservative Stabilisers	0.09% Sodium Azide (NaN3)2% Sucrose
Immunogen	Synthetic peptide corresponding to the N-terminal region of human CREB binding protein
Acknowledgements	PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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技术参数

产品应用 WB

产品类型 PrecisionAb Polyclonal

推荐用于 WB

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Rabbit anti Human CREB binding protein antibody 伯乐 VPA00303 CREB binding protein抗体

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