Rabbit anti Human UBE2D1 antibody 伯乐 VPA00296 UBE2D1抗体

2024-10-28

Rabbit anti Human UBE2D1 antibody

货号:VPA00296

规格:100 uL

市场价格:2890

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:UBE2D1

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti Human UBE2D1 antibodyrecognizes UBE2D1, also known as UBC4/5 homolog, stimulator of Fe transport, ubiquitin carrier protein D1, ubiquitin-conjugating enzyme E2 D1, ubiquitin-conjugating enzyme E2-17 kDa 1 and ubiquitin-protein ligase D1.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. The UBE2D1 gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for UBE2D1 (provided by RefSeq, Mar 2011).Rabbit anti Human UBE2D1 antibody detects a band of 17 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target SpeciesHuman
Product FormIg fraction - liquid
PreparationRabbit Ig fraction prepared by ammonium sulphate precipitation.
Buffer SolutionPhosphate buffered saline.
Preservative Stabilisers0.09% Sodium Azide (NaN3).
ImmunogenKLH-conjugated synthetic peptide corresponding to aa 111-140 of human UBE2D1
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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技术参数

产品应用 WB

产品类型 PrecisionAb Polyclonal

推荐用于 WB

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