Goat anti TDP-43 伯乐TDP-43抗体 VPA00030

2024-10-28

Goat anti TDP-43

货号:VPA00030

规格:100 µl

市场价格:3613

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:TDP-43

物种:人

宿主:山羊

抗体亚型:IgG

荧光染料:Purified

产品介绍
Goat anti Human TDP-43 antibodyrecognizes human TAR DNA-binding protein 43, also known as TDP-43, the product of the TAR DNA-binding protein 43 gene. TDP-43 is a 414 amino acid DNA and RNA binding protein containing 2RRMdomains involved in regulation of transcription and splicing. TDP-43 is ubiquitously expressed with high levels being seen in pancreas, gall bladder, alimentary tract, reproductive system, adipose tissue, skin and skeletal muscle.Mutations in the TPD43 gene are implicated in development of Amyotrophic lateral sclerosis 10, a neurodegenerative disorder affecting motor neurons leading to eventual fatal paralysis (Van Deerlinet al.2008).Goat anti Human TDP-43 antibody recognizes human TDP-43 as a single band of ~45kDa in multiple cell line lysates by western blotting under reducing conditions. The antibody also cross-reacts with rodent cell line lysates tested.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationGoat polyclonal antibody purified by ammonium sulfate precipitation followed by antigen affinity chromatography.
Buffer SolutionTRIS buffered saline.
Preservative Stabilisers0.02% Sodium Azide (NaN3)0.5% Bovine Serum Albumin
ImmunogenPeptide sequence C-HISNAEPKHNSNRQ from an internal region of TDP-43.
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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技术参数

产品应用 WB

产品类型 PrecisionAb Polyclonal

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