Goat anti Human NPM antibody 伯乐VPA00058 人 抗体 WB

2024-10-28

Goat anti Human NPM antibody

货号:VPA00058

规格:100 µl

市场价格:4055

产品类型:免疫组化一抗

品牌:Bio-Rad

物种:人/小鼠

宿主:山羊

抗体亚型:IgG

荧光染料:Purified

产品介绍
Goat anti Human NPM antibodyrecognizes NPM, also known as nucleophosmin. NPM is a major nucleolar phosphoprotein expressed at notably higher levels in proliferating and tumor cells, compared to resting cells. It plays important roles in ribosome biogenesis, centrosome duplication and cell proliferation.NPM is a mobile protein which shuttles between the nucleolus and cytoplasm depending upon growth conditions and ATP/GTP levels, and is also influenced by cytotoxic drugs including actinomycin D and camptothecin. NPM interacts with numerous proteins including p19ARF, transcription factor YY1 and nucleolar p120, and is known to regulate the stability and transcriptional activity of p53, a tumor suppressor protein activated in response to DNA damage, capable of inducing cell cycle arrest and apoptosis.Goat anti Human NPM antibody detects nucleophosmin as a single band of 38 kDa in a range of human cell lysates tested.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationGoat polyclonal antibody purified by affinity chromatography.
Buffer SolutionTRIS buffered saline.
Preservative Stabilisers0.02% Sodium Azide (NaN3)0.5% Bovine Serum Albumin
ImmunogenPeptide with sequence C-QEAIQDLWQWRKSL from the C terminus of the protein sequence.
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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技术参数

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