Mouse anti Human YY1 antibody BIO-RAD VMA00573 YY1 antibody

2024-10-28

Mouse anti Human YY1 antibody

货号:VMA00573

规格:100μl

市场价格:2780

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:YY1

物种:人

宿主:小鼠

抗体亚型:IgG1

克隆号: CD02/2B2

荧光染料:Purified

产品介绍
Mouse anti Human YY1 antibodyrecognizes the transcriptional repressor protein YY1, also known as INO80 complex subunit S or Yin and Yang 1 protein.The protein YY1 is a ubiquitously-expressed zinc finger transcription factor which can act as an activator or repressor of transcription under different circumstances (Galloway et al. 2017). In addition to transcriptional regulation, YY1 is involved with cell proliferation, chromatin remodeling and apoptosis. Many targets of YY1, for example ERBB2 and p53, are involved with cancer pathogenesis (Kaufhold et al. 2016). Accordingly, YY1 is overexpressed in multiple cancer types, and overexpression is correlated with poor prognosis (Cho and Bonavida 2017). YY1 may be inhibited by siRNA, proteasome inhibitors, and a variety of other factors. Inhibition of YY1 has been suggested as a potential target in cancer (Bonavida 2017).
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationMouse monoclonal antibody purified by affinity chromatography on Protein G from tissue culture supernatant.
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.09% Sodium Azide (NaN3).
ImmunogenE. coli-derived recombinant human YY1 (amino acids 1 - 414)
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch.
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting1/1000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.Flow CytometryUse 10ul of the suggested working dilution to label 106cells or 100ul human whole blood.
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技术参数

产品应用 IP ;WB

产品类型 多克隆抗体

推荐用于 IP; WB

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