Mouse anti Human APEX1 antibody BIO-RAD VMA00561 APEX1 antibody

2024-10-28

Mouse anti Human APEX1 antibody

货号:VMA00561

规格:100μl

市场价格:2916

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:APEX1

物种:人

宿主:小鼠

抗体亚型:IgG1

克隆号:CPTC15

荧光染料:Purified

产品介绍
Mouse anti Human APEX1 antibodyrecognizes the apurinic/apyrimidinic endodeoxyribonuclease 1, also known as AP endonuclease class I, AP lyase or protein REF-1.Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. The APEX1 gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein (provided by RefSeq, Jul 2008).Mouse anti Human APEX1 antibody detects a band of 36 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationMouse monoclonal antibody purified by affinity chromatography on Protein G from ascites.
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.09% Sodium Azide (NaN3).
ImmunogenRecombinant protein of human APEX1
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch.
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting1/1000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.Flow CytometryUse 10ul of the suggested working dilution to label 106cells or 100ul human whole blood.
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产品类型 多克隆抗体

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