Mouse anti Human BAK antibody BIO-RAD VMA00527 Mouse anti Human BAK antibody

2024-10-28

Mouse anti Human BAK antibody

货号:VMA00527

规格:100μl

市场价格:2890

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:BAK

物种:人

宿主:小鼠

抗体亚型:IgG2a

克隆号:AB04/1A2

荧光染料:Purified

产品介绍
Mouse anti Human BAK antibodyrecognizes the Bcl-2 homologous antagonist/killer, also known as BAK, BCL2-like 7 protein, apoptosis regulator BAK, bcl2-L-7 or pro-apoptotic protein BAK.The protein encoded by BAK1 gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress (provided by RefSeq, Jul 2008).Mouse anti Human BAK antibody detects a band of 25 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationMouse monoclonal antibody purified by affinity chromatography on Protein G from tissue culture supernatant.
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.09% Sodium Azide (NaN3).
ImmunogenE. coli-derived recombinant human BAK (amino acids 29 - 187)
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch.
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting1/1000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.Flow CytometryUse 10ul of the suggested working dilution to label 106cells or 100ul human whole blood.
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技术参数

产品应用 wb

产品类型 单克隆抗体

推荐用于 wb

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