Mouse anti Human MAPK9 / JNK2 antibody BIO-RAD VMA00323 Mouse anti Human MAPK9 / JNK2 antibody

2024-10-28

Mouse anti Human MAPK9 / JNK2 antibody

货号: VMA00323

规格:100μl

市场价格:3205

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:MAPK9 / JNK2

物种:人

宿主:小鼠

抗体亚型:IgG1, kappa

克隆号:OTI1A1

荧光染料:Purified

产品介绍
Mouse anti Human MAPK9 / JNK2 antibodyrecognizes the mitogen-activated protein kinase 9, also known as Jun kinase, MAP kinase 9, c-Jun N-terminal kinase 2, c-Jun kinase 2, stress-activated protein kinase 1a and stress-activated protein kinase JNK2.Encoded by the MAPK9 (JNK2) gene, mitogen-activated protein kinase 9 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. MAPK9 and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. MAPK9's mouse counterpart suggests a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported (provided by RefSeq, Sep 2008).Mouse anti Human MAPK9 antibody detects a band of 54 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationMouse monoclonal antibody purified by affinity chromatography from ascites.
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.09% Sodium Azide (NaN3).
ImmunogenFull length recombinant human MAPK9 (NP_620707) produced in HEK293T cells
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch.
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting1/1000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.Flow CytometryUse 10ul of the suggested working dilution to label 106cells or 100ul human whole blood.
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产品类型 单克隆抗体

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