Mouse anti Human AXL receptor tyrosine kinase antibody BIO-RAD VMA00320 Mouse anti Human AXL receptor tyrosine kinase anti

2024-10-28

Mouse anti Human AXL receptor tyrosine kinase antibody

货号:VMA00320

规格:100μl

市场价格:2916

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:AXL receptor tyrosine kinase

物种:人

宿主:小鼠

抗体亚型:IgG1

克隆号:7E10

荧光染料:Purified

产品介绍
Mouse anti Human AXL receptor tyrosine kinase antibodyrecognizes the AXL oncogene, also known as AXL transforming sequence/gene and tyrosine-protein kinase receptor UFO.Encoded by the AXL gene, the AXL oncogene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. It possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). AXL may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of AXL (provided by RefSeq, Jul 2013).Mouse anti Human AXL receptor tyrosine kinase antibody detects a band of 138 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationMouse monoclonal antibody prepared by affinity chromatography on Protein G from ascites.
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.09% Sodium Azide (NaN3).
ImmunogenPurified recombinant extracellular fragment of human AXL receptor tyrosine kinase fused with hIgGFc tag expressed in the HEK293 cell line
Approx. Protein ConcentrationsIgG concentration 0.5 mg/ml.
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch.
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting1/1000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.Flow CytometryUse 10ul of the suggested working dilution to label 106cells or 100ul human whole blood.
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产品应用 wb,IP

产品类型 单克隆抗体

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