Mouse anti Human TATA-box-binding protein antibody BIO-RAD VMA00301 Mouse anti Human TATA-box-binding protein antibody-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Mouse anti Human TATA-box-binding protein antibody BIO-RAD VMA00301 Mouse anti Human TATA-box-binding protein antibody

2024-10-28

Mouse anti Human TATA-box-binding protein antibody

货号：VMA00301

规格：100μl

市场价格：2916

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：TATA-box-binding protein

物种：人

宿主：小鼠

抗体亚型：IgG1

克隆号：830CT4.3.3

荧光染料：Purified

产品介绍
Mouse anti Human TATA-box-binding protein antibodyrecognizes the TATA-box-binding protein, also known as TATA sequence-binding protein, TATA-box binding protein N-terminal domain, TATA-box factor and transcription initiation factor TFIID TBP subunit.Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TBP gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 32-39, and expansion of the number of repeats increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease. Two transcript variants encoding different isoforms have been found for TBP (provided by RefSeq, Feb 2010)Mouse anti Human TATA-box-binding protein antibody detects a band of 40 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Mouse monoclonal antibody prepared by affinity chromatography on Protein G from ascites.
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	0.09% Sodium Azide (NaN3).
Immunogen	Purified His-tagged TATA-box-binding protein
Acknowledgements	PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory	For research purposes only
Guarantee	12 months from date of despatch.
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√	1/1000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.Flow CytometryUse 10ul of the suggested working dilution to label 106cells or 100ul human whole blood.
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技术参数

产品应用 wb

产品类型单克隆抗体

推荐用于 wb

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Mouse anti Human TATA-box-binding protein antibody BIO-RAD VMA00301 Mouse anti Human TATA-box-binding protein antibody

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