Mouse anti Human ALIX antibody BIO-RAD VMA00273 Mouse anti Human ALIX antibody-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Mouse anti Human ALIX antibody BIO-RAD VMA00273 Mouse anti Human ALIX antibody

2024-10-28

Mouse anti Human ALIX antibody

货号：VMA00273

规格：100μl

市场价格：4335

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：ALIX

物种：人

宿主：小鼠

抗体亚型：IgG2a

克隆号：OTI1A4

荧光染料：Purified

产品介绍
Mouse anti Human ALIX antibodyrecognizes the programmed cell death 6-interacting protein, also known as ALG-2 interacting protein 1, ALG-2-interacting protein X, PDCD6-interacting protein, apoptosis-linked gene 2-interacting protein X, dopamine receptor interacting protein 4 and programmed cell death 6-interacting protein.The PDCD6IP (ALIX) gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Overexpression of murine ALIX can block apoptosis. In addition, the product of PDCD6IP binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. PDCD6IP (ALIX) product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of PDCD6IP product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for PDCD6IP. Related pseudogenes have been identified on chromosome 15 (provided by RefSeq, Jan 2012).Mouse anti Human ALIX antibody detects a band of 96 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Mouse monoclonal antibody purified by affinity chromatography from ascites.
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	0.09% Sodium Azide (NaN3)1% Bovine Serum Albumin≤50% Glycerol
Immunogen	Full length recombinant human ALIX (NP_037506) produced in HEK293T cells
Acknowledgements	PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory	For research purposes only
Guarantee	12 months from date of despatch.
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√		1/1000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.Flow CytometryUse 10ul of the suggested working dilution to label 106cells or 100ul human whole blood.
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Mouse anti Human ALIX antibody BIO-RAD VMA00273 Mouse anti Human ALIX antibody

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