Recombinant Human CD253 BIO-RAD Recombinant Human CD253-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Recombinant Human CD253 BIO-RAD Recombinant Human CD253

2024-10-29

Recombinant Human CD253

货号：PHP125

规格：50 µg

市场价格：3470

产品类型：细胞因子添加物

品牌：Bio-Rad

产品介绍
Recombinant human CD253is a 19.6 kDa protein comprised of 168 amino acids which correspond to the TNF-homologous region of the extracellular domain of human TRAIL/ApoL2.TNF-related apoptosis-inducing ligand (TRAIL) is expressed in many tissues including spleen, lung and prostate (Wileyet al, 1995) and is capable of inducing apoptosis in a tumor specific manner (Walczaket al, 1997). Apoptosis is initiated by the binding of the two death receptors DR4 and DR5 which initiate cell death signaling via the caspase cascade. There are however two decoy receptors DcR1 and DcR2 which competitively bind to CD253 but do not initiate apoptosis (Allen and El-Deiry, 2012).A potential use for TRAIL as an anti-tumor therapeutic agent has been identified, demonstrating tumoricidal activity in approximately two thirds of tumor cell lines tested (Griffithet al, 1999).Recombinant human CD253 is the immunogen used to produce Rabbit anti human CD253 (AHP1215).
产品详情
Target Species	Human
Product Form	Purified recombinant protein - lyophilized
Reconstitution	Reconstitute with 0.1 ml distilled water. For extended storage, the addition of 0.1% BSA is recommended.Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution.
Preservative Stabilisers	None present
Carrier Free	Yes
Purity	>98% by SDS PAGE and HPLC analysis
Protein Molecular Weight	19.6kD (169 amino acid sequence)
Approx. Protein Concentrations	0.5 mg/ml after reconstitution.
Regulatory	For research purposes only
Guarantee	Guaranteed for 3 months from the date of reconstitution or until the date of expiry, whichever comes first. Please see label for expiry date.
存储条件
Prior to reconstitution store at -20℃. Following reconstitution store at -20℃.This product should be stored undiluted.Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application Name	Verified	Min Dilution	Max Dilution
Functional Assays	√	0.2
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

技术参数

产品应用 elisa，wb，fn

产品类型重组蛋白

推荐用于 elisa，wb，fn

© bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪是专业的授权总代理区域代理经销平台。
© 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
© 本文地址：https://gibcohyclone.cn/thread-50818.htm

特别声明：以上内容(如有图片亦包括在内)来源于授权厂家或网络，如有侵权，请联系删除，本平台不提供信息存储服务。

Notice: The content above (including the pictures if any)comes from authorized manufacturers or networks. In case of infringement, please contact to delete it. This platform does not provide information storage services.

产品询价需求提交

Recombinant Human CD253 BIO-RAD Recombinant Human CD253

相关推荐