Mouse anti human CD47 antibody, clone BRIC126 BIO-RAD MCA911T Mouse anti human CD47 antibody, clone BRIC126

2024-10-29

Mouse anti human CD47 antibody, clone BRIC126

货号:MCA911T,MCA911

规格:25 µg,0.2 mg

市场价格:893,3783

产品类型:流式抗体

品牌:Bio-Rad

抗原:CD47

物种:人

宿主:小鼠

抗体亚型:IgG2b

克隆号:BRIC126

荧光染料:Purified

产品介绍
Mouse anti human CD47 antibody, clone BRIC126recognises the human CD47 cell surface glycoprotein, a heavily N-glycosylated 47-52 kDa molecule. CD47 is expressed on all cells and tissues so far examined, although expression is reduced on erythrocytes of the rare Rh null phenotype.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationPurified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer SolutionTRIS buffered glycine
Preservative Stabilisers<0.1% Sodium Azide (NaN3)
Approx. Protein ConcentrationsPack Size: 0.2 mgIgG concentration 1 mg/mlPack Size: 25 µgIgG concentration 1.0 mg/ml
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application NameVerifiedMin DilutionMax Dilution
Flow Cytometry
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Avent, N.et al.(1988) Monoclonal antibodies that recognize different membrane proteins that are deficient in Rhnull human erythrocytes. One group of antibodies reacts with a variety of cells and tissues whereas the other group is erythroid-specific.Biochem J. 251 (2): 499-505.2.Ide, K.et al.(2007) Role for CD47-SIRPalpha signaling in xenograft rejection by macrophages.Proc Natl Acad Sci U S A. 104 (12): 5062-6.3.Lecchi, C.et al.(2008) Bovine alpha-1 acid glycoprotein can reduce the chemotaxis of bovine monocytes and modulate CD18 expression.Vet Res. 39: 50.4.Chao, M.P.et al.(2011) Therapeutic antibody targeting of CD47 eliminates human acute lymphoblastic leukemia.Cancer Res. 71 (4): 1374-84.

技术参数

产品应用 Flow;WB

产品类型 Monoclonal Antibody

推荐用于 Flow;WB

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