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  3. Mouse anti Human CD36 antibody, clone SMØ BIO-RAD MCA722T Mouse anti Human CD36 antibody, clone SMØ

Mouse anti Human CD36 antibody, clone SMØ BIO-RAD MCA722T Mouse anti Human CD36 antibody, clone SMØ

2024-10-29
Mouse anti Human CD36 antibody, clone SMØ

货号：MCA722T,MCA722GA,MCA722

规格：25 µg,0.1 mg,0.2 mg

市场价格：935,2023,3315

产品类型：流式抗体

品牌：Bio-Rad

抗原：CD36

物种：人

宿主：小鼠

抗体亚型：IgM

克隆号：SMØ

荧光染料：Purified

产品介绍
Mouse anti Human CD36 antibody, clone SMØrecognizes the CD36 antigen, an ~88 kDa cell surface glycoprotein expressed by platelets, monocytes/macrophages and also by some microvascular endothelium and erythroid precursors.CD36 is the receptor for thrombospondin. When expressed by monocytes and macrophages, CD36 acts as a receptor for oxidized LDL and for apoptotic polymorphonuclear cells. Mouse anti Human CD36 antibody, clone SMØ partially inhibits collagen induced platelet aggregation and macrophage ingestion of apoptotic human neutrophils. It has been reported that this antibody may activate platelets as measured by fibrinogen binding, P-Selectin expression and Annexin V binding - for further details please contact our Technical Services team.Mouse anti Human CD36 antibody, clone SMØ is also reported to block interaction of oxidized low-density lipoprotein (OXLDL) with CD36 (Sugiharaet al.1992).
产品详情
Target SpeciesHuman
Product FormPurified IgM - liquid
PreparationPurified IgM prepared by ammonium sulphate precipitation from tissue culture supernatant
Buffer SolutionPhosphate buffered saline
ImmunogenHuman tonsil cells and peripheral blood mononuclear cells.
Preservative Stabilisers0.09%Sodium Azide
Carrier FreeYes
Approx. Protein ConcentrationsIgG concentration 1.0 mg/ml
Fusion PartnersSpleen cells from immunised mice were fused with cells of the NSI mouse myeloma line.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store at +4℃.DO NOT FREEZE.This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application NameVerifiedMin DilutionMax Dilution
Flow Cytometry√1/50Pack Size: 0.2 mg1/10Pack Size: 0.1 mg
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Hogg, N.et al.(1984) Monoclonal antibodies specific for human monocytes, granulocytes and endothelium.Immunology. 53 (4): 753-67.2.Sarigianni, M.et al.(2010) Effect of leptin and insulin resistance on properties of human monocytes in lean and obese healthy participants.Angiology. 61: 768-74.3.Sugihara, K.et al.(1992) Thrombospondin mediates adherence of CD36+ sickle reticulocytes to endothelial cells.Blood. 80 (10): 2634-42.4.Biswas, A.K.et al.(2007) Plasmodium falciparum uses gC1qR/HABP1/p32 as a receptor to bind to vascular endothelium and for platelet-mediated clumping.PLoS Pathog. 3: 1271-80.

技术参数

产品应用 Flow

产品类型 Monoclonal Antibody

推荐用于 Flow

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