mouse anti human HLA DP DQ DR:StarBright Blue 700

货号：MCA477SBB700

规格：100 Tests/0.5ml

市场价格：3808

产品类型：流式抗体

品牌：Bio-Rad

抗原：HLA DP DQ DR

物种：人

宿主：小鼠

抗体亚型：IgG2a, kappa

克隆号：WR18

荧光染料：其它

类型:	单抗	同型对照：	IgG2a
浓度：		用法：	5 µL/test(Flow)
免疫原性：	Human HLA Class II (DP, DQ, DR).

Mouse anti Human HLA DP DQ DR antibody, clone WR18reacts with a monomorphic determinant common to DP, DQ and DR beta chains, which are expressed by antigen presenting cells, B cells, monocytes and activated T lymphocytes.The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region. There are 3 major MHC class II proteins encoded by the HLA which are HLA DP, HLA DQ and HLA DR.

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参考文献：

1. Moore, K.et al. (1987) Use of the monoclonal antibody WR17, identifying the CD37 gp40-45 Kd antigen complex, in the diagnosis of B-lymphoid malignancy.J Pathol 152:13-21.2. Kissner, T.L.et al.(2011) Activation of MyD88 Signaling upon Staphylococcal Enterotoxin Binding to MHC Class II Molecules.PLoS One. 6: e15985.3. Chia, J.S.et al.(2001) Human T-cell responses to the glucosyltransferases ofStreptococcus mutans.Clin Diagn Lab Immunol. 8: 441-5.4. Chang, Y.C.et al.(2008) Epigenetic control of MHC class II expression in tumor-associated macrophages by decoy receptor 3.Blood. 111: 5054-63.5. Litzinger, M.T.et al.(2009) Chronic lymphocytic leukemia (CLL) cells genetically modified to express B7-1, ICAM-1, and LFA-3 confer APC capacity to T cells from CLL patients.Cancer Immunol Immunother. 58: 955-65.6. Sadallah, S.et al.(2011) Microparticles (ectosomes) shed by stored human platelets downregulate macrophages and modify the development of dendritic cells.J Immunol. 186: 6543-52.7. Sabbah, S.et al.(2012) T-cell immunity to Kaposi sarcoma-associated herpesvirus: recognition of primary effusion lymphoma by LANA-specific CD4+ T cells.Blood. 119 (9): 2083-92.8. John, J.et al.(2010) Differential effects of Paclitaxel on dendritic cell function.BMC Immunol. 11:14.9. Palmer, K.J.et al.(2000) Interferon-alpha (IFN-alpha) stimulates anti-melanoma cytotoxic T lymphocyte (CTL) generation in mixed lymphocyte tumour cultures (MLTC).Clin Exp Immunol. 119: 412-8.10. Silk, K.M.et al.(2012) Rapamycin conditioning of dendritic cells differentiated from human ES cells promotes a tolerogenic phenotype.J Biomed Biotechnol. 2012: 172420.

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