Mouse anti Bovine GFAP BIO-RAD MCA4733GA Mouse anti Bovine GFAP-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Mouse anti Bovine GFAP BIO-RAD MCA4733GA Mouse anti Bovine GFAP

2024-10-29

Mouse anti Bovine GFAP

货号：MCA4733GA,MCA4733

规格：0.1 mg,0.25 mg

市场价格：2151,3162

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：GFAP

物种：其它

宿主：小鼠

抗体亚型：其它

荧光染料：Alexa Fluor 488

产品介绍
Mouse anti Bovine GFAP antibody, clone 1B4recognizes glial fibrillary acidic protein, or GFAP, a class III intermediate filament. During development of the central nervous system, GFAP distinguishes astrocytes from other glial cells. It is involved in various cellular functions, such as cell structure and movement, cell communication and the functioning of the blood-brain barrier. It also plays a role in mitosis by adjusting the filament network present in the cell.Defects in GFAP are a cause of Alexander disease, a rare disorder of the central nervous system affecting mostly males. It is a progressive leukoencephalopathy resulting in mental and physical retardation, dementia, seizures and early death.Mouse anti Bovine GFAP antibody, clone 1B4 may be used in conjunction with clones4A11and2E1for increased sensitivity when used in immunohistology.
产品详情
Target Species	Bovine
Product Form	Purified IgG - liquid
Preparation	Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	0.09% Sodium Azide (NaN3)
Immunogen	Bovine spinal cord homogenate.
Approx. Protein Concentrations	IgG concentration 1.0mg/ml
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√	1/25
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Pegram, C.N.et al.(1985) Monoclonal antibodies reactive with epitopes restricted to glial fibrillary acidic proteins of several species.Neurochem Pathol. 3 (2): 119-38.2.McLendon, R.E.et al.(1986) The immunohistochemical application of three anti-GFAP monoclonal antibodies to formalin-fixed, paraffin-embedded, normal and neoplastic brain tissues.J Neuropathol Exp Neurol. 45 (6): 692-703.3.Schwabenlander, M.et al.(2016) Brain, Craniofacial, and Dental Lesions of a Free-ranging Gray Wolf (Canis lupus) Implicated in a Human Attack in Minnesota, USA.J Wildl Dis. 52 (1): 131-7.

技术参数

产品应用 Flow

产品类型单克隆抗体

推荐用于 Flow

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Mouse anti Bovine GFAP BIO-RAD MCA4733GA Mouse anti Bovine GFAP

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