mouse anti human CD279 伯乐人CD279抗体 MCA4624GA-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

mouse anti human CD279 伯乐人CD279抗体 MCA4624GA

2024-10-29

mouse anti human CD279

货号：MCA4624GA

规格：0.1 mg

市场价格：4590

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：CD279

物种：人

宿主：小鼠

抗体亚型：IgG2b

克隆号：4F12

荧光染料：Purified

产品介绍
Mouse anti Human CD279, clone 4F12recognizes human CD279, otherwise known as PD-1/PDCD1, a type I transmembrane glycoprotein and member of the Ig superfamily, which acts as a co-stimulatory molecule and negative regulator of T-cell activation (Patsoukiset al.2012).CD279 is an immunoinhibitory receptor which interacts with its ligands CD274 (PD-L1) and CD273 (PD-L2) to inhibit the activation and proliferation of T and B cells. CD279 is associated with regulating peripheral tolerance of T cells and preventing autoimmunity and autoimmune diseases, including type I diabetes and rheumatoid arthritis (Okazakiet al.2005).
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Purified IgG prepared by affinity chromatography on Protein G from ascites
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	0.02% Sodium Azide (NaN3)10% Glycerol
Immunogen	Recombinant human CD279 (amino acids 21-167) purified fromEscherichia coli.
Approx. Protein Concentrations	IgG concentration 1.0 mg/ml
Fusion Partners	Spleen cells from immunised Balb/c mice were fused with cells of the mouse FO myeloma cell line.
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√	1/500
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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技术参数

产品应用 ELISA;WB

产品类型 Monoclonal Antibody

推荐用于 ELISA;WB

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mouse anti human CD279 伯乐 人CD279抗体 MCA4624GA

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mouse anti human CD279 伯乐人CD279抗体 MCA4624GA