Rat anti Mouse CD1d BIO-RAD MCA4700 Rat anti Mouse CD1d

2024-10-29

Rat anti Mouse CD1d

货号:MCA4700

规格:0.25 mg

市场价格:3086

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:CD1d

物种:人

宿主:大鼠

抗体亚型:IgG1, kappa

荧光染料:Alexa Fluor 488

产品介绍
Rat anti Mouse CD1d antibody, clone 1B1recognizes mouse CD1d, a glycoprotein expressed on cortical thymocytes, certain T cell leukemias and various other antigen presenting cells. CD1d binds self and non-self glycolipids and presents them to T cell receptors on natural killer cells. When activated, natural killer cells produce Th1 and Th2 cytokines.
产品详情
Target SpeciesMouse
Product FormPurified IgG - liquid
PreparationPurified IgG prepared by affinity chromatography
Buffer SolutionPhosphate buffered saline
ImmunogenMouse CD1d cDNA-transfected RMA-S mouse T lymphoma
Preservative Stabilisers0.09%Sodium Azide
Approx. Protein ConcentrationsIgG concentration 0.5mg/ml
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application NameVerifiedMin DilutionMax Dilution
Flow Cytometry1/10
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Sun, J.et al.(2010) Deficiency of antigen-presenting cell invariant chain reduces atherosclerosis in mice.Circulation 122 (8): 808-20.2.Zhou, Z.et al.(2011) Autoreactive marginal zone B cells enter the follicles and interact with CD4+ T cells in lupus-prone mice.BMC Immunol. 12: 7.3.Soh, S. Y.et al.(2016) NKT Cell Hyporesponsiveness Leads to Unrestrained Accumulation of Marginal Zone B Cells in Hypercholesterolemic Apolipoprotein E-Deficient Mice.The Journal of Immunology. Oct 21 [Epub ahead of print].

技术参数

产品应用 Flow

产品类型 单克隆抗体

推荐用于 Flow

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