mouse anti Rat CD252 伯乐 MCA4634 CD252 抗体

2024-10-29

mouse anti Rat CD252

货号:MCA4634

规格:0.25 mg

市场价格:3018

产品类型:流式抗体

品牌:Bio-Rad

抗原: CD252

物种:大鼠

宿主:小鼠

抗体亚型:IgG1, kappa

克隆号:ATM-2

荧光染料:Purified

产品介绍
Mouse anti Rat CD252 antibody, clone ATM-2recognizes rat CD252, otherwise known as OX40L or CD134L, a ~22 kDa type II transmembrane glycoprotein and member of the TNF superfamily, expressed by antigen-presenting cells including activated dendritic cells and B cells, and also by vascular endothelium.The interaction of CD252 with its receptor OX40/CD134, acts as a co-stimulator of T cell activation, proliferation and both Th1 and Th2 cytokine production, and is also important in activated B cell proliferation and secretion of immunoglobulins (Igs). CD252/OX40 interaction has been implicated in HTLV-1 associated diseases including myelopathy and adult T cell leukaemia, and also with the autoimmune diseases rheumatoid arthritis and inflammatory bowel disease.Mouse anti Rat CD252 antibody, clone ATM-2 has been shown to block the co-stimulatory activity of CD252 on rat T cell proliferation.
产品详情
Target SpeciesRat
Product FormPurified IgG - liquid
PreparationPurified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.09% Sodium Azide (NaN3)
ImmunogenACI-S1 rat T-cell lymphoma cell line.
Approx. Protein ConcentrationsIgG concentration 1.0mg/ml
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light.
应用
Application NameVerifiedMin DilutionMax Dilution
Flow Cytometry
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Satake, Y.et al.(2000) Characterization of rat OX40 ligand by monoclonal antibody.Biochem Biophys Res Commun. 270 (3): 1041-8.

技术参数

产品应用 E

产品类型 单克隆抗体

推荐用于 E

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