Rat anti Mouse CD36 antibody, clone MF3 BIO-RAD MCA2748GA Rat anti Mouse CD36 antibody, clone MF3-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rat anti Mouse CD36 antibody, clone MF3 BIO-RAD MCA2748GA Rat anti Mouse CD36 antibody, clone MF3

2024-10-29

Rat anti Mouse CD36 antibody, clone MF3

货号：MCA2748GA,MCA2748

规格：0.1 mg,0.25 mg

市场价格：2057,3162

产品类型：流式抗体

品牌：Bio-Rad

抗原：CD36

物种：小鼠

宿主：大鼠

抗体亚型：IgG2a

克隆号：MF3

荧光染料：Purified

产品介绍
Rat anti Mouse CD36 antibody, clone MF3recognizes mouse CD36, also known as platelet glycoprotein 4, glycoprotein IIIb or PAS IV. CD36 is an ~85 kDa multipass transmembrane glycoprotein primarily expressed on platelets, monocytes/macrophages, smooth muscle and endothelial cells. The CD36 molecule is type B scavenger receptor, which binds to multiple ligands including thrombospondin, anionic phospholipids, oxidized low density lipoproteins and long chain fatty acids.CD36 has diverse functions and is reported to play a role in innate immunity, platelet adhesion/aggregation and long chain fatty acid transport. The CD36 molecule also directly mediates cytoadhesion of erythrocytes infected withPlasmodium falciparum, and may be involved in the development of atherosclerotic lesions and the formation of foam cells.Rat anti Mouse CD36 antibody, clone MF3 has been shown to inhibit IL-4 induced thioglycollate-elicited peritoneal macrophage fusion and significantly block IL-4/GM-CSF-induced bone-marrorw derived macrophage fusion.
产品详情
Target Species	Mouse
Product Form	Purified IgG - liquid
Preparation	Purified IgG prepared by affinity chromatography on Protein G
Buffer Solution	Phosphate buffered saline
Carrier Free	Yes
Preservative Stabilisers	0.09% Sodium Azide (NaN3)
Approx. Protein Concentrations	IgG concentration 1 mg/ml
Immunogen	IL-4 treated murine thioglycollate-elicited peritoneal macrophages
Fusion Partners	Spleen cells from immunised DA rats were fused with cells of the Y3Ag 1.2.3 myeloma cell line
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Helming, L.et al.(2009) The scavenger receptor CD36 plays a role in cytokine-induced macrophage fusion.J Cell Sci. 122 (Pt 4): 453-9.2.Mwaikambo, B.R.et al.(2009) Hypoxia up-regulates CD36 expression and function via hypoxia-inducible factor-1- and phosphatidylinositol 3-kinase-dependent mechanisms.J Biol Chem. 284: 26695-707.3.Yang, C.N.et al.(2011) Mechanism mediating oligomeric Aβ clearance by naïve primary microglia.Neurobiol Dis. 42 (3): 221-30.4.Seeds, R.E.et al.(2011) The role of myeloid receptors on murine plasmacytoid dendritic cells in induction of type I interferon.Int Immunopharmacol. 11: 794-801.5.Samovski, D.et al.(2012) Insulin and AMPK regulate FA translocase/CD36 plasma membrane recruitment in cardiomyocytes via Rab GAP AS160 and Rab8a Rab GTPase.J Lipid Res. 53 (4): 709-17.

技术参数

产品应用 Flow

产品类型 Monoclonal Antibody

推荐用于 Flow

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Rat anti Mouse CD36 antibody, clone MF3 BIO-RAD MCA2748GA Rat anti Mouse CD36 antibody, clone MF3

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