mouse anti human C3a 伯乐 mouse anti human C3a MCA2604-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

mouse anti human C3a 伯乐 mouse anti human C3a MCA2604

2024-10-29

mouse anti human C3a

货号：MCA2604

规格：0.1 ml

市场价格：6248

产品类型：流式抗体

品牌：Bio-Rad

抗原：C3a

物种：人

宿主：小鼠

抗体亚型：IgG1

克隆号：048-18.6.3.X (10-21)

荧光染料：Purified

产品介绍
Mouse anti Human C3a antibody, clone 048-18.6.3.X (10-21)recognizes the ~9 kDa complement component 3a (C3a) which is present in the blood serum. C3a is generated over the course of complement activation where complement 3 (C3) convertases cleave C3 to C3a and C3b, which is further degraded into iC3b and C3dg/C3d. C3 is crucial in the induction of tolerance generated when an antigen is introduced into immunoprivileged sites and this is exploited by pathogens and cancer cells to evade the immune system by inhibiting complement activation.C3a mediates local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C3a is expressed at significantly higher levels in colorectal cancer.Mouse anti Human C3a antibody, clone 10-21 shows minimal reactivity with other complement proteins in radioimmunoassays and haemagglutination.Mouse anti Human C3a antibody, clone 10-21 has been reported to work in western blotting applications.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Purified IgG prepared by affinity chromatography on Protein A from ascites
Buffer Solution	Borate buffered saline
Immunogen	Native purified human C3a.
Approx. Protein Concentrations	Current, batch-specific concentration 1.1 mg/ml
Preservative Stabilisers	0.1% Sodium Azide (NaN3)
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light.
应用
Application Name	Verified	Min Dilution	Max Dilution
ELISA	√	1/1500
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
推荐产品
Description	Product Code	Applications	Pack Size
Mouse IgG1 Negative Control	MCA928	F	100 Tests/1ml
文献
1.Hugli, T.E. (1975) Human anaphylatoxin (C3a) from the third component of complement. Primary structure.J Biol Chem. 250 (21): 8293-301.2.Habermann, J.K.et al.(2006) Increased serum levels of complement C3a anaphylatoxin indicate the presence of colorectal tumors.Gastroenterology. 131 (4): 1020-9; quiz 1284.

技术参数

产品应用 ELISA;WB

产品类型单克隆抗体

推荐用于 ELISA;WB

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mouse anti human C3a 伯乐 mouse anti human C3a MCA2604

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