Rat anti mouse CDw199 伯乐mouse CDw199 MCA2586GA-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rat anti mouse CDw199 伯乐mouse CDw199 MCA2586GA

2024-10-29

Rat anti mouse CDw199

货号： MCA2586GA

规格：0.1 mg

市场价格：2108

产品类型：流式抗体

品牌：Bio-Rad

抗原：CDw199

物种：小鼠

宿主：大鼠

抗体亚型：IgG2a

克隆号：9B1

荧光染料：Purified

产品介绍
Rat anti Mouse CD199 antibody, clone 9B1detects mouse chemokine receptor 9 (CCR9), also known as CD199. CCR9 is a seven transmembrane protein which is a member of the beta chemokines receptor family. CCR9 is expressed in thymus and small intestine, and mediates the recruitment and development of thymocytes in response to CCL25; the only known ligand of CCR9.CCR9 is an alternative co-receptor with CD4 for HIV infection, and has been implicated in adult T cell leukaemia. Two alternatively spliced transcript variants have been described.Clone 9B1 blocks CCL25-induced Ca2+release, attenuating inflammation in a murine model of chronic ileitis when given in early disease stages.
产品详情
Target Species	Mouse
Product Form	Purified IgG - liquid
Preparation	Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution	Phosphate buffered saline
Immunogen	25 amino acids from the amino terminal of murine CCR9, coupled to KLH.
Approx. Protein Concentrations	IgG concentration 1.0mg/ml
Preservative Stabilisers	0.09%Sodium Azide
Fusion Partners	Spleen cells from immunised Lewis rat were fused with cells of the X63-Ag8.653 myeloma cell line.
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√	1/25
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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Description	Product Code	Applications	Pack Size
Rat IgG2a Negative Control	MCA1212	F	1ml
文献
1.Rivera-nieves, J.et al.(2006) Antibody blockade of CCL25/CCR9 ameliorates early but not late chronic murine ileitis.Gastroenterology. 131 (5): 1518-29.2.Nagakubo, D.et al.(2007) Expression of CCR9 in HTLV-1+ T cells and ATL cells expressing Tax.Int J Cancer. 120 (7): 1591-7.

技术参数

产品应用 Flow

产品类型 Monoclonal Antibody

推荐用于 Flow

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Rat anti mouse CDw199 伯乐mouse CDw199 MCA2586GA

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