mouse anti human CD172g:FITC 伯乐 mouse anti human CD172g:FITC

2024-10-29

mouse anti human CD172g:FITC

货号:MCA2584F

规格:0.1 mg

市场价格:3213

产品类型:流式抗体

品牌:Bio-Rad

抗原:CD172g

物种:人

宿主:小鼠

抗体亚型:IgG1

克隆号:OX119

荧光染料:FITC

产品介绍
Mouse anti Human CD172g antibody, clone OX119recognizes human SIRP gamma, a 55 kDa signal regulatory protein which is a member of the immunoglobulin gene superfamily. SIRP gamma, also known as CD172g, is expressed on most T lymphocytes and a subset of B-cells but is absent on myeloid cells. CD172g has a truncated cytoplasmic tail, which is similar to SIRP beta, but unlike SIRP beta CD172g does not require DAP12 for expression at the cell surface. CD172g, like SIRP alpha, binds to CD47 inducing apoptosis. It is also involved in the negative regulation of receptor tyrosine kinase-coupled signalling.
产品详情
Target SpeciesHuman
Product FormPurified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
PreparationPurified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer SolutionPhosphate buffered saline
ImmunogenPurified recombinant SIRPgamma.CD4.
Approx. Protein ConcentrationsIgG concentration 0.1mg/ml
Preservative Stabilisers0.09%Sodium Azide1%Bovine Serum Albumin
Max Ex/EmFluorophoreExcitation Max (nm)Emission Max (nm)
FITC490525
Fusion PartnersSpleen cells from immunised BALB/c mice were fused with cells of the NS-1 myeloma cell line.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light.
应用
Application NameVerifiedMin DilutionMax Dilution
Flow CytometryNeat
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Brooke, G.et al. (2004) Human lymphocytes interact directly with CD47 through a novel member of the signal regulatory protein (SIRP) family.J Immunol.173:2562-70.

技术参数

产品应用 Flow

产品类型 单克隆抗体

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