Mouse anti Human CD87 antibody, clone VIM-5 BIO-RAD MCA2516A488T Mouse anti Human CD87 antibody, clone VIM-5-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Mouse anti Human CD87 antibody, clone VIM-5 BIO-RAD MCA2516A488T Mouse anti Human CD87 antibody, clone VIM-5

2024-10-29

Mouse anti Human CD87 antibody, clone VIM-5

货号：MCA2516A488T,MCA2516A488

规格：25 Tests/0.25ml,100 Tests/1ml

市场价格：1403,3162

产品类型：流式抗体

品牌：Bio-Rad

抗原：CD87

物种：人

宿主：小鼠

抗体亚型：IgG1

克隆号：VIM-5

荧光染料：Alexa Fluor 488

产品介绍
Mouse anti Human CD87 antibody, clone VIM-5recognizes human CD87, also known as urokinase plasminogen activator receptor (uPAR), a 50-65 kDa single chain glycosylphostidylinsitol (GPI) anchored glycoprotein, expressed by granulocytes, tissue macrophages, monocytes, endothelial cells, fibroblasts and mesenchymal and epithelial tumour cells.CD87 specifically binds and activates urokinase plasminogen activator (uPA), a serine protease which converts the inactive receptor-bound proenzyme plasminogen into plasmin, triggering the proteolysis cascade of fibrinolysis. The interaction between uPAR and uPA is also known to play a role in cancer cell invasion and metastasis.Clone VIM-5 is reported to block urokinase binding.
产品详情
Target Species	Human
Product Form	Purified IgG conjugated to Alexa Fluor 488 - liquid
Preparation	MCA2516A488T: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant MCA2516A488: Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Buffer Solution	Phosphate buffered saline
Immunogen	THP-1 cells (Human acute monocytic leukaemia cells).
Preservative Stabilisers	0.09% Sodium Azide (NaN3)1% Bovine Serum Albumin
Approx. Protein Concentrations	IgG concentration 0.05 mg/ml
Max Ex/Em	Fluorophore	Excitation Max (nm)	Emission Max (nm)
Alexa Fluor®488	495	519
Acknowledgements	This product is provided under an intellectual property licence from Life Technologies Corporation. The transfer of this product is contingent on the buyer using the purchase product solely in research, excluding contract research or any fee for service research, and the buyer must not sell or otherwise transfer this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; (c) manufacturing or quality assurance or quality control, or (d) resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad CA 92008 USA or outlicensing@thermofisher.com
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√	Neat
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
文献
1.Sillaber, C.et al.(1997) Molecular and functional characterization of the urokinase receptor on human mast cells.J Biol Chem. 272 (12): 7824-32.2.Gadd, S.J.et al.(1990) M5, a phosphoinositol-linked human myelomonocytic activation-associated antigen.Clin Exp Immunol. 80 (2): 252-6.

技术参数

产品应用 Flow

产品类型 Monoclonal Antibody

推荐用于 Flow

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Mouse anti Human CD87 antibody, clone VIM-5 BIO-RAD MCA2516A488T Mouse anti Human CD87 antibody, clone VIM-5

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