Rat anti Mouse CD41 antibody, clone MWReg30 BIO-RAD MCA2245P647 Rat anti Mouse CD41 antibody, clone MWReg30-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rat anti Mouse CD41 antibody, clone MWReg30 BIO-RAD MCA2245P647 Rat anti Mouse CD41 antibody, clone MWReg30

2024-10-29

Rat anti Mouse CD41 antibody, clone MWReg30

货号：MCA2245P647

规格：100 Tests/1ml

市场价格：3162

产品类型：流式抗体

品牌：Bio-Rad

抗原：CD41

物种：小鼠

宿主：大鼠

抗体亚型：IgG1

克隆号：MWReg30

荧光染料：Alexa Fluor 647

产品介绍
Rat anti Mouse CD41 antibody, clone MWReg30recognizes the mouse integrin alpha IIb subunit CD41. CD41 is a ~125 kDa single pass type 1 transmembrane glycoprotein expressed by platelets, megakaryocytes (Zhanget al.2007), mast cells (Berlangaet al.2005), and hematopoietic progenitors (Mitjavila-Garciaet al.2002). CD41 forms a heterodimer withCD61.The CD41/CD61 complex is important for platelet adhesion and aggregation (Patelet al.2003) acting as a receptor for many extracellular matrix proteins including fibronectin, thrombospondin and vitronectin (Weiselet al.1992).Rat anti mouse CD41, clone MWReg30 has been reported to inhibit PMA induced aggregationin vitroand to induce hypothermiain vivo(Nieswandtet al.1999).
产品详情
Target Species	Mouse
Product Form	Purified IgG conjugated to RPE-Alexa Fluor 647 - lyophilized
Preparation	Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution	Phosphate buffered saline
Immunogen	Purified murine platelets
Preservative Stabilisers	0.09% Sodium Azide (NaN3)1% Bovine Serum Albumin5% Sucrose
Approx. Protein Concentrations	IgG concentration 0.05 mg/ml
Max Ex/Em	Fluorophore	Excitation Max (nm)	Emission Max (nm)
RPE-Alexa Fluor®647 488nm laser	496	667
Acknowledgements	This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is contingent on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not sell or otherwise transfer this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; (c) manufacturing or quality assurance or quality control, or (d) resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√	Neat
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
文献
1.Nieswandt, B.et al.(1999) Acute systemic reaction and lung alterations induced by an antiplatelet integrin gpIIb/IIIa antibody in mice.Blood. 94 (2): 684-93.

技术参数

产品应用 Flow

产品类型 Monoclonal Antibody

推荐用于 Flow

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Rat anti Mouse CD41 antibody, clone MWReg30 BIO-RAD MCA2245P647 Rat anti Mouse CD41 antibody, clone MWReg30

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