mouse anti human CD29 伯乐 MCA1949T CD29抗体

2024-10-29

mouse anti human CD29

货号:MCA1949T ,MCA1949GA,MCA1949

规格:25 µg,0.1 mg,0.2 mg

市场价格:893,2023,3315

产品类型:流式抗体

品牌:Bio-Rad

抗原: CD29

物种:人

宿主:小鼠

抗体亚型:IgG1, kappa

克隆号:4B7R

荧光染料:Purified

产品介绍
Mouse anti Human CD29 monoclonal antibody, clone 4B7Rrecognizes the human integrin beta 1 subunit, also known as CD29, a ~130 kDa (red) 115 kDa (non-red) single pass type I transmembrane glycoprotein expressed by most leucocytes andmesenchymal stem cells.Integrin receptors are involved in the regulation of a variety of important biological functions, including embryonic development, wound repair, hemostasis and prevention of programmed cell death. They are also implicated in abnormal pathological states such as tumor directed angiogenesis, tumor cell growth, and metastasis. Surface expression of CD29 on human natural killer cells can be reduced by pretreatment with the glutathione-S-transferase inhibitor diethyl maleate (Horvath-Arcidiaconoet al.2003)
产品详情

Target Species

Human

Product Form

Purified IgG - liquid

Preparation

  • MCA1949GA, MCA1949: Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant

  • MCA1949T: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

BufferSolution

Phosphate buffered saline

Preservative Stabilisers

0.09% Sodium Azide (NaN3)

Carrier FreeYes

Immunogen

Occular melanoma cell line V+B2.

Approx. Protein ConcentrationsIgG concentration 1.0 mg/ml

Regulatory

For research purposes only

Guarantee

12 monthsfrom dateof despatch

存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application NameVerifiedMin DilutionMax Dilution

Flow Cytometry

1/251/50
Immunofluorescence
Immunohistology - Paraffin1
Immunoprecipitation
Western BlottingX
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications fromthe originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.1This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls
  • Flow CytometryUse 10ul of the suggested working dilution to label 106cells in 100ul.
同型
DescriptionProduct CodeApplicationsPack Size
Mouse IgG1 Negative Control

MCA928

F100 Tests/1ml
文献
1. Tan, D.W.et al.(2013) Single-cell gene expression profiling reveals functional heterogeneity of undifferentiated human epidermal cells.Development. 140 (7): 1433-44.2. Yang, J.et al.(2015) Cordycepin protected against the TNF-α-induced inhibition of osteogenic differentiation of human adipose-derived mesenchymal stem cells.Int J Immunopathol Pharmacol. 28 (3): 296-307.3. Gu, Q.et al.(2015)Ginkgo bilobaextract promotes osteogenic differentiation of human bone marrow mesenchymal stem cells in a pathway involving Wnt/β-catenin signaling.Pharmacol Res. 97: 70-8.4. Chen, Y.et al.(2015) Effect of human umbilical cord mesenchymal stem cells transplantation on nerve fibers of a rat model of endometriosis.Int J Fertil Steril. 9 (1): 71-80.5. Lee, H.J.et al.(2017) ICOSL expression in human bone marrow-derived mesenchymal stem cells promotes induction of regulatory T cells.Sci Rep. 7: 44486.6. Yi, T.et al.(2015) Manufacture of Clinical-Grade Human Clonal Mesenchymal Stem Cell Products from Single Colony Forming Unit-Derived Colonies Based on the Subfractionation Culturing Method.Tissue Eng Part C Methods. 21 (12): 1251-62.7. Sun, Y.et al.(2017) Antinociceptive Effect of Intrathecal Injection of Genetically Engineered Human Bone Marrow Stem Cells Expressing the Human Proenkephalin Gene in a Rat Model of Bone Cancer Pain.Pain Res Manag. 2017: 7346103.8. Kim, S.H.et al.(2019) Forkhead box O1 (FOXO1) controls the migratory response of Toll-like receptor (TLR3)-stimulated human mesenchymal stromal cells.J Biol Chem. 294 (21): 8424-37.

技术参数

产品应用 Flow; IF ;IP;IHC( P )*

产品类型 Monoclonal Antibody

推荐用于 Flow; IF ;IP;IHC( P )*

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