mouse anti GROWTH CONE 伯乐 MCA1712 GROWTH CONE 抗体

2024-10-29

mouse anti GROWTH CONE

货号:MCA1712

规格:2 ml

市场价格:3596

产品类型:流式抗体

品牌:Bio-Rad

抗原:GROWTH CONE

物种:其它

宿主:小鼠

抗体亚型:IgM

克隆号:2G13

荧光染料:Purified

产品介绍

Mouse anti Growth Cone antibody, clone 2G13recognizes a protein originally termed 2G13P which is localized to growth cones. Subsequent investigation has identified this protein to be 40S ribosomal protein SA, also known as 37 kDa laminin receptor precursor or Laminin receptor 1 (Balouiet al.2004). 40S ribosomal protein SA is a 296 amino acid ~37 kDa membrane, cytoplasmic and nuclear protein required for the assembly and/or stability of the 40S ribosomal subunit.. In vertebrate evolution the molecule has acquired a secondary function as a laminin receptor (UniProt: P50890). In growth cones expression is notable particularly in filopodia and lamellipodia in developing rat CNS and embryonic neurons in culture (Stettleret al.1999).40S ribosomal protein SA interacts with the filamentous actin cytoskeleton and therefore may be involved in growth cone motility (Stettleret al.1999). Mouse anti Growth Cone antibody, clone 2G13 has been used for the detection of growth cones by immunohistochemistry and identification of 40S ribosomal protein SA by western blotting in chicken and rat samples (Balouiet al.2004).
产品详情

Target Species

Chicken

Species Cross-ReactivityTarget SpeciesCross Reactivity
Rat
Mouse
N.B. Antibody reactivity and working conditions may vary between species.

Product Form

Tissue Culture Supernatant - liquid

Preparation

Tissue Culture Supernatant containing 0.2M Tris/HClpH7.4 and 5-10% foetal calf serum

Preservative Stabilisers

0.09% Sodium Azide

ImmunogenEmbryonic chick tectal membranes.
Fusion PartnersSpleen cells from immunised mice were fused with cells of the mouse NS1 myeloma cell line.

Regulatory

For research purposes only

Guarantee

12 months from date of despatch

存储条件

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

应用

Application Name

Verified

Min Dilution

Max Dilution

Flow Cytometry

X

Immunohistology - Frozen
Immunohistology - Paraffin
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. Clone 2G13 has also been reported to work in Western Blotting.
  • ImmunohistologyThis product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections.
数据

Immunohistochemical staining of growth cones of primary olfactory neurons within the olfactory bulb in the developing rat brain using Mouse anti growth cone antibody (MCA1712).

相关产品

Description

Product Code

Applications

Pack Size

Mouse anti Chicken CD184 / CXCR4

MCA6012GA

IHC;IF

0.1 mg

文献
1. Baloui, H.et al.(2004) Cellular prion protein/laminin receptor: distribution in adult central nervous system and characterization of an isoform associated with a subtype of cortical neurons.Eur J Neurosci. 20 (10): 2605-16.2. Espejo, C.et al.(2005) Time-course expression of CNS inflammatory, neurodegenerative tissue repair markers and metallothioneins during experimental autoimmune encephalomyelitis.Neuroscience. 132(4):1135-49.3. Penkowa, M.et al.(2003) Metallothionein-I overexpression alters brain inflammation and stimulates brain repair in transgenic mice with astrocyte-targeted interleukin-6 expression.Glia. 42 (3): 287-306.4. Kim, S.R.et al.(2011) Dopaminergic pathway reconstruction by Akt/Rheb-induced axon regeneration.Ann Neurol. 70: 110-20.5. Nordman, J.C. & Kabbani, N. (2012) An interaction between α7 nicotinic receptors and a G-protein pathway complex regulates neurite growth in neural cells.J Cell Sci. 125 (Pt 22): 5502-13.

技术参数

产品应用 IHC

产品类型 Monoclonal Antibody

推荐用于 IHC

© bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪是专业的授权总代理区域代理经销平台。
© 如需询价,请加客服QQ:1749072012 、客服微信:jinshanbio,或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务,数据资源基于CC协议。
© 本文地址:https://gibcohyclone.cn/thread-53702.htm
产品询价需求提交
返回
扫码添加客服微信,咨询产品报价