mouse anti human CD120a 伯乐 MCA1340 CD120a抗体-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

mouse anti human CD120a 伯乐 MCA1340 CD120a抗体

2024-10-29

mouse anti human CD120a

货号：MCA1340,MCA1340T

规格：0.2 mg,25 µg

市场价格：3868,935

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：CD120a

物种：人

宿主：小鼠

抗体亚型：IgG1, kappa

克隆号：H398

荧光染料：Purified

产品介绍
Mouse anti Human CD120a antibody, clone H398recognizes an extracellular domain of the ~55 kDa human TNF receptor (p55, TNF-R1, CD120a). No binding occurs to the ~75 kDa TNF receptor (CD120b). CD120a is weakly expressed by monocytes and granulocytes.Mouse anti Human CD120a antibody, clone H398 may be used to detect high levels of TNFR1, in western blotting under reducing conditions, such as recombinant material, but it is not suitable for detection of TNFR1 in normal cells in this application.Mouse anti Human CD120a antibody, clone H398 inhibits the biological activity of both natural and recombinant human TNFalpha and TNFbeta (Thomaet al.1990andDriet al.1999).Mouse anti Human CD120a antibody, clone H398 is routinely tested in flow cytometry on human peripheral blood monocytes.
产品详情
Target Species	Human
Species Cross-Reactivity	Target Species	Cross Reactivity
Rabbit	√
N.B. Antibody reactivity and working conditions may vary between species.
Product Form	Purified IgG - liquid
Preparation	Purified IgG prepared by affinity chromatography on Protein A
BufferSolution	Phosphate buffered saline
Preservative Stabilisers	<0.1% Sodium Azide (NaN3)
Immunogen	Purified human tumour necrosis factor receptor type 1.
Approx. Protein Concentrations	IgG concentration 1.0 mg/ml
Fusion Partners	Spleen cells from immunized BALB/c mice were fused with cells of the mouse NS0 myeloma cell line.
Regulatory	For research purposes only
Guarantee	12 monthsfrom date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Radioimmunoassays	√
ELISA	√
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications fromthe originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
文献
1. Gregory, A.P.et al.(2012) TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis.Nature. 488 (7412): 508-11.2. Schett, G.et al.(2003) TNFalpha mediates susceptibility to heat-induced apoptosis by protein phosphatase-mediated inhibition of the HSF1/hsp70 stress response.Cell Death Differ. 10: 1126-36.3. Buckley, C.D.et al.(2005) Identification of a phenotypically and functionally distinct population of long-lived neutrophils in a model of reverse endothelial migration.J Leukoc Biol.79: 303-11.4. Thiery, J.et al.(2003) Potentiation of a tumor cell susceptibility to autologous CTL killing by restoration of wild-type p53 function.J Immunol. 170: 5919-26.5. Lin, K.H.et al.(2009) Mechanisms of resveratrol-induced platelet apoptosis.Cardiovasc Res. 83: 575-85.6. Baker, P.K.et al.(2012) Response of hairy cells to IFN-alpha involves induction of apoptosis through autocrine TNF-alpha and protection by adhesion.Blood. 100: 647-53.7. Nakamura-Lopez, Y.et al.(2015) RSV P-protein impairs extrinsic apoptosis pathway in a macrophage-like cell line persistently infected with respiratory syncytial virus.Virus Res. 204: 82-7.8. Yang, F.et al.(2013) Improved retinal ganglion cell survival through retinal microglia suppression by a chinese herb extract, triptolide, in the DBA/2J mouse model of glaucoma.Ocul Immunol Inflamm. 21 (5): 378-89.

技术参数

产品应用 ELISA;RIA

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mouse anti human CD120a 伯乐 MCA1340 CD120a抗体

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