BIO-RAD MCA71R Rat anti Human HLA DR,Rat anti Human HLA DR antibody, clone YE2/36-HLK-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

BIO-RAD MCA71R Rat anti Human HLA DR,Rat anti Human HLA DR antibody, clone YE2/36-HLK

2024-10-22

Rat anti Human HLA DR antibody, clone YE2/36-HLK

货号：MCA71R

规格：0.25 mg

价格：3553

产品类型：流式抗体

品牌：Bio-Rad

抗原：HLA DR

物种：人

宿主：大鼠

抗体亚型：IgG2a

克隆号：YE2/36-HLK

荧光染料：Purified

产品介绍
Rat anti Human HLA DR antibody, clone YE2/36-HLKrecognizes a monomorphic determinant of human HLA DR which is an MHC class II cell surface receptor expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages and activated T lymphocytes.The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region. There are 3 major MHC class II proteins encoded by the HLA which are HLA DP, HLA DQ and HLA DR.Rat anti Human HLA DR antibody, clone YE2/36-HLK has also been reported to be cross reactive with mouse H-2 haplotypes b, d and q expressed by mouse strains including C57BL/6, DBA, and NZB (Brickellet al.1981).
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Purified IgG prepared by affinity chromatography on Protein G
Buffer Solution	Phosphate buffered saline
Immunogen	EHR-B Ramos cells.
Preservative Stabilisers	0.09%Sodium Azide
Approx. Protein Concentrations	IgG concentration 1.0 mg/ml
Fusion Partners	Spleen cells from immunised AO rats were fuzed with cells of the rat Y3 Ag1.2.3 myeloma cell line.
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√	1/50
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Brickell, P.M.et al. (1981) A monoclonal antibody to the HLA-DR product recognizes a polymorphic Ia determinant in mice.Immunology. 43: 493-501.2.Whiteland, J.L.et al.(1995) Immunohistochemical detection of T-cell subsets and other leukocytes in paraffin-embedded rat and mouse tissues with monoclonal antibodies.J Histochem Cytochem. 43 (3): 313-20.3.Bellinghausen, I.et al. (2003) Production of interleukin-13 by human dendritic cells after stimulation with protein allergens is a key factor for induction of T helper 2 cytokines and is associated with activation of signal transducer and activator of transcription-6.Immunology. 108:167-176.4.Thorne, A.et al.(2015) Tumor necrosis factor-α promotes survival and phenotypic maturation of poly(I:C)-treated dendritic cells but impairs their Th1 and Th17 polarizing capability.Cytotherapy. pii: S1465-3249(14)00857-3.

技术参数

产品应用 Flow

产品类型 Monoclonal Antibody

推荐用于 Flow

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BIO-RAD MCA71R Rat anti Human HLA DR,Rat anti Human HLA DR antibody, clone YE2/36-HLK

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