BIO-RAD MCA715GT Rat anti Human CD59 antibody, clone YTH53.1,Rat anti Human CD59 antibody, clone YTH53.1-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

BIO-RAD MCA715GT Rat anti Human CD59 antibody, clone YTH53.1,Rat anti Human CD59 antibody, clone YTH53.1

2024-10-22

Rat anti Human CD59 antibody, clone YTH53.1

货号：MCA715GT,MCA715G

规格：25 µg,0.2 mg

价格：893,3315

产品类型：流式抗体

品牌：Bio-Rad

抗原：CD59

物种：人

宿主：大鼠

抗体亚型：IgG2b

克隆号：YTH53.1

荧光染料：Purified

产品介绍
Rat anti Human CD59 antibody, clone YTH53.1recognizes the human CD59 cell surface antigen, also known as MAC-inhibitory protein, 1F5 antigen, 20 kDa homologous restriction factor, MEM43 antigen, membrane attack complex inhibition factor, membrane inhibitor of reactive lysis or protectin. CD59 is produced as a 103 amino acid proprotein, further processed to produce an 18-20 kDa GPI linked glycoprotein broadly expressed by human leucocytes and erythrocytes.Mutation of the CD59 gene can result in the presentation of Hemolytic anemia, CD59-mediated, with or without polyneuropathy (HACD59) a disease characterized by infantile onset of a relapsing-remitting polyneuropathy manifest as limb muscle weakness, and hyporeflexia.Rat anti Human CD59 antibody, clone YTH53.1 blocks the normal function of CD59 (Walshet al.1991).
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution	Phosphate buffered saline
Immunogen	Human Peripheral Blood T cells.
Preservative Stabilisers	0.09%Sodium Azide
Approx. Protein Concentrations	IgG concentration 1.0 mg/ml
Fusion Partners	Spleen cells from an immunised DA rat were fused with cells of the Y3/Ag1.2.3 rat myeloma cell line.
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Davies, A.et al.(1989) CD59, an LY-6-like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells.J Exp Med. 170 (3): 637-54.2.Walsh, L.A.et al.(1991) Transfection of human CD59 complementary DNA into rat cells confers resistance to human complement.Eur J Immunol. 21 (3): 847-50.3.Davies, A.et al.(1995) Identification of MIC 11 antigen as an epitope of the CD59 molecule.Immunology. 85 (2): 220-7.4.Ellison BSet al.(2007) Complement susceptibility in glutamine deprived breast cancer cells.Cell Div. 2: 20.

技术参数

产品应用 Flow

产品类型 Monoclonal Antibody

推荐用于 Flow

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BIO-RAD MCA715GT Rat anti Human CD59 antibody, clone YTH53.1,Rat anti Human CD59 antibody, clone YTH53.1

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