BIO-RAD MCA5965GA Mouse anti Human IL-27α, clone H08-5C8,Mouse anti Human IL-27α, clone H08-5C8-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

BIO-RAD MCA5965GA Mouse anti Human IL-27α, clone H08-5C8,Mouse anti Human IL-27α, clone H08-5C8

2024-10-22

Mouse anti Human IL-27α, clone H08-5C8

货号：MCA5965GA

规格：0.1 mg

价格：2576

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：IL-27α

物种：人

宿主：小鼠

抗体亚型：IgG1

克隆号：H08-5C8

荧光染料：Purified

产品介绍
Mouse anti Human IL-27α, clone H08-5C8,recognizes IL-27α, a subunit of IL-27. IL-27 is a 62 kDa member of the Il-6/IL-12 family of long type I cytokines. IL-27 is heterodimeric group 2 receptor composed of Epstein-Barr Virus induced gene 3 (EBI3) and IL-27α. EBI3 is a 34 kDa glycoprotein that is related to the p40 subunit of IL-12 and IL-23 and IL-27α is a 28 kDa glycoprotein that is related to the p35 of chain IL-12.IL-27 has broad range of pro- and anti-inflammatory properties, mediating its effects via its gp130-associated cytokine receptor and JAK/STAT signalling cascades. It can alter T helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells and has diverse effects on innate immune cells.In vivo, it is reported to play an important role in immune regulation, as mice with defects in IL-27 or its receptor display enhanced immune responses (Batten & Ghilardi 2007).
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Purified IgG prepared by affinity chromatography on Protein G from ascites
Buffer Solution	Phosphate buffered saline
Immunogen	NS0-derived recombinant human IL-27
Fusion Partners	Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line
Preservative Stabilisers	<0.1% Sodium Azide (NaN3)
Approx. Protein Concentrations	IgG concentration 1.0 mg/ml
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
ELISA	√
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Batten, M. & Ghilardi, N. (2007) The biology and therapeutic potential of interleukin 27J Mol Med (Berl). 85: 661-72.

技术参数

产品应用 Elisa

产品类型 Monoclonal Antibody

推荐用于 Elisa

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BIO-RAD MCA5965GA Mouse anti Human IL-27α, clone H08-5C8,Mouse anti Human IL-27α, clone H08-5C8

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