Bio-Rad PAPILLOMAVIRUS 16 ONCOprotein E7 MCA2819,mouse anti human PAPILLOMAVIRUS 16 ONCOprotein E7

2024-10-22

mouse anti human PAPILLOMAVIRUS 16 ONCOprotein E7

货号:MCA2819

规格:0.2 mg

价格:3018

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:PAPILLOMAVIRUS 16 ONCOprotein E7

物种:Virus

宿主:小鼠

抗体亚型:IgG1

克隆号:716-F10

荧光染料:Purified

产品介绍
Mouse anti Human Papillomavirus 16 Oncoprotein E7 antibody, clone 716-F10recognizes both the monomer and dimer forms of the E7 oncoprotein of human papilloma virus 16. Human papillomavirus (HPV) is a diverse group of DNA-based viruses that infect skin and mucous membranes of humans and animals. Some HPV types are the causative agents of cervical cancer, with types 16 and 18 being particularly high-risk. The viral proteins E6 and E7 disrupts normal cell cycle regulation by interacting with p53 (a tumor-suppressing transcription factor) and Rb (retinoblastoma protein, also a tumor-supressor). E7 particularly binds to Rb and histone deacetylases, resulting in activation of the E2F genes, which code for a family of transcription factors. The viral proteins E6 and E7 might be of particular interest in the development of therapeutic vaccines, since they are expressed early in viral infection.Mouse anti Human Papillomavirus 16 Oncoprotein E7 antibody, clone 716-F10 does not cross-react with E7 protein of HPV-18.
产品详情
Target SpeciesViral
Product FormPurified IgG - liquid
PreparationPurified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers<0.1% Sodium Azide (NaN3)
ImmunogenOncoprotein E7 from human papillomavirus 16,
Approx. Protein ConcentrationsIgG concentration 1.0mg/ml
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application NameVerifiedMin DilutionMax Dilution
ELISA
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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技术参数

产品应用 ELISA;WB

产品类型 单克隆抗体

推荐用于 ELISA;WB

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